I think there are some good casinos to invest, you can choose one of them or few of them and start investing, good luck.
Sure, picking a popular casino is one small part of choosing a good site to invest on, but there are many other factors you'd need to look out for.
Haven't you seen that graph on the first page of this thread? That gives you a pretty good overview of what casino's are interesting for investments.
If you like steady profits without much risk, Crypto-Games is clearly the way to go... Stats don't lie.
The problem with crypto-games is that they have a lot of fees for your transactions there. If you don't invest long term then they will charge you when you withdraw your investment and also they charge a hefty miner's fee since they do not shoulder it. I tried investing 0.2 btc with them, I profited about 5% and lost the 5% in fees. So no point in investing there.
They're worth it.
I have invested in 5 bitcoin casinos bankroll, and most of them haven't turned a profit at all.
This month all casinos I have invested in are in a loss, except for Crypto-Games.
Previously some have turned a profit, but not even as close as Crypto-Games.
Currently I have investments there, on SafeDice and YoloDice, nothing more right now.
However both SafeDice and YoloDice are negative this month, and I can't say profits were big previously.
CG has turned over 5%/month, which is bloody awesome.