What are the practical chances of getting screwed if one accepts a zeroconf transaction with Bitcoin (ie. Blockchain.info shows it)?
I'm guessing that also the thrust of the OP is that faster blocks allow for faster transactions at a point of sale, especially physical shops where the customer walks out of the store immediately after paying.
Last month I did my first
wave-and-pay transaction on my Visa card, which does not even require require a pin number for small amounts. It took 1 second and was done. There is no way a decentralized cryptocurrency will ever compete with that in terms of waiting for block confirmations. This is why Litecoin's 2.5 minute block time is not a significant benefit.
The solution for immediate sales (zero confirmations) must lie elsewhere. Merchants can accept the double-spend risk as a cost of doing business just as they accept the risk of forged currency or stolen credit cards today. In the future there might be insurance available against double-spends for an annual premium. 3rd-party applications which run on top of the Bitcoin protocol can enable instant confirmations if the customer and merchant both use the same 3rd-party service (this is probably a future role for the CC companies).