in target of shortcut :
D:\DarkcoinMN\darkcoin-qt.exe -datadir=D:\DarkcoinMNData -wallet=XXXX
Blockchain will be in specific location on different drive (D drive in this case) using commandline -datadir
wallet.dat needs to be renamed as XXXX to work..
Yes, someone can start his multiple masternodes with different shortcuts
Shortcut1 target - C:\Users\Administrator\Desktop\darkcoin-qt.exe -datadir=D:\Darkcoin -conf=mn1.conf -wallet=mn1.dat
Shortcut2 target - C:\Users\Administrator\Desktop\darkcoin-qt.exe -datadir=D:\Darkcoin -conf=mn2.conf -wallet=mn2.dat
Shortcut3 target - C:\Users\Administrator\Desktop\darkcoin-qt.exe -datadir=D:\Darkcoin -conf=mn3.conf -wallet=mn3.dat
...
Where mn1, mn2, mn3.dat.. are the masternode wallets and mn1, mn2, mn3.conf are their config files.