First, there will always be a bigger threat to cryptos than regulation, and that's quantum computing.
I can't get into major details in regards to this, so i'm only going to address regulation in the sense for coin launches.
There are 3 things to consider when ICO's get regulated: innovation, capital/investments/monetary gain for the country and competition. Competition in the sense of owning an industry (U.S. and silicon valley, China and manufacturing... etc). How many trillions of dollars has silicon valley brought to the U.S.? Could blockchain one day be on this scale, who knows. But regulation will ultimately dictate these factors.
Crypto will eventually be entirely regulated, but not in the common sense, because innovation is always occurring and there will be coins that launch that double down on the fundamentals of decentralization, anonymity and etc. In the truest sense, cryptos will never be regulated by their nature. And if people want to use crypto anonymous, there will be nothing governments can do. They can't ever control a blockchain and all that. It will require a whole special oversight and branches of government to oversee cryptos, so it's essentially a futile effort in that regard. Transactions can't be controlled, the system can't be controlled and the user's sending (anonymous coins) can't be idenitifed. These are major problems that will never be solved within the next decade.
The only way a government can fully control a "threat" or blockchain in general, is to ban it all-together or allocate enough resources to track down individuals through blockchain, which is very difficult/impossible, especially if someone intentionally hid their tracks or used anonymous coins, aka Monero.
On the flip side with ICOs
Governments have to be very very careful not to stifle this industry, because blockchain technology will create thousands of jobs and bring in significant capital, along with the prestige of being at the edge of technology (for the country). This is why i actually appreciate with how the U.S. is approaching this, small steps at a time, figuring out small ways to implement rules before they go big dick and issue big executive decisions. I don't agree with all their decisions though, and i think there will always be ignorance and resentment towards blockchain tech, this is another problem for another day though.
In regards to regulation for ICO's and coin launches, regulation will be good and bad. Again, it will stifle innovation and may chase the entire industry out of a country, so regulations have to accommodate competition among governments and "be friendly" to these operators, or else they'll completely lose the entire industry from their country. You can already see this occuring, how come ICO's don't get launched in the U.S. and how many innovators did they stifle by introducing the SEC into ICO's, regulating that. A fatal mistake for the U.S. and same goes with China.
Now ICO's are mainly getting launched from European/South American countries and Russia. Soon that will not be the case either. So, what i predict what will occur is the volume of ICO's will all be consolidated into a few countries who are ICO friendly, and thus the volume of coins launching will eventually be dramatically reduced. Now, there will always be coin launches and people who won't abide by these rules, but i'm disregarding them for this post.
This topic is very broad, and this is just a glimpse of what will occur and circumstances that could arise with coin launches only (obviously there are regulations for exchanges, traders, investors, illegal activity, taxes... list goes on). The entire debate will occur for a long time, and in the meantime, Blockchain tech and some crypto's will outlive governments and generations of people. This is the reality.