If anyone else has any good advice for me, I'd greatly appreciate it--and I did read this thread. Hardware wallets are new to me and I'm not sure what the pitfalls are, if any.
There aren't too many pitfalls really... and the Ledger Nano S is a decent enough piece of kit.
Aside from all the normal advice of making sure the device is reset and generating a new seed mnemonic/PIN/Passphrase etc... I would also advise that BEFORE you send any crypto to the device, make sure you're comfortable with wiping it and restoring from the 24 word seed mnemonic.
Basically, install Ledger Live, connect the device and follow the instructions for setting it up. Then note down the receiving address(es) given. Then wipe the device (there is an option in the settings or you can simply enter an incorrect PIN 3 times)... the restore from the 24 word seed mnemonic and confirm that you see the same receiving address(es) following the restore.
This will give you piece of mind that:
1. You have correctly written down the WHOLE seed mnemonic (from memory, the initial setup only confirms a couple of the words at random).
2. The restore functionality works as advertised without risking any coins.
When I got mine, I actually created a couple of different seeds and checked against things like Ian Coleman's BIP39 mnemonic converter to make sure that it was creating "proper" mnemonics, before I wiped and then created the "final" one.
Also, try installing, deleting and reinstalling the coin apps on the device to get comfortable with how the "Manager" functionality in Ledger Live works and see that even if you remove an app and then reinstall, you still get the same addresses etc.
Finally, just an FYI, by default, Ledger will give Nested Segwit addresses for BTC. You can also create "Legacy" if you want and apparently the native Segwit support is in final stages of release... for now, I believe native segwit is still marked as "experimental".