This would be right now about 65.000 Dollar.
1. Would you cash out everything?
2. Would you invest in 5 new icos with each 20 Bitcoins and hold long term (12 - 24 month) and hoping that some of that 5 icos will double your 20 Bitcoins again 10x or more times? = 500 or more Bitcoins
3. Would you invest in altcoins?
It would be better to cash out or reserve the half then reroll the other half. In case some of these investment in ICO failed, you still have fund to pull to invest it again to another one and get profit. Buying altcoin is an option but why would someone keep an altcoin while you have the most trusted crypto in hand. Trade it maybe then convert it to bitcoin once profit is realized.