Just edited your OP to make it more understandable, trading of altcoin to be profitable has to do with, how informed you are as a trader and what are you chances of making the right call in regards to buying or selling your bag due to your speculation of what a news effect will have on the price of the altcoins. The altcoin market unlike that of bitcoin is mostly motivated by hype (a marketing strategy employed by altcoin to promote their project) irrespective of how legitimate or quality an altcoin is, without any hype of the project it becomes a dead project or goes under the radar away from the mainstream media.
The best strategy has to do with buying the rumors (that's why I said you have to stay informed) if a project is getting listed on a high volume exchange anything soon it's a clear sign some hype will come towards that project which will reflect on the price of the coins so as a trader your job is to take advantage of that opportunity to by the rumors in anticipation of the news to sell (take profit).