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Topic: Human trials of corona virus vaccine (Read 301 times)

legendary
Activity: 3990
Merit: 1385
July 16, 2020, 11:10:16 AM
#29
In my opinion, we all need to develop a natural immunity against coronavirus but without vaccines, let alone compulsory ones. Weak people have always died and will continue to die and there is no stopping this process. Personally, I don't care what I die from. It's a natural selection and only it can make us stronger.

As you said, "Weak people have always died and will continue to die and there is no stopping this process." The part you missed a little is, even the extremely strong people all become weak. Then it happens to them, too, because they aren't strong anymore.

Cool
legendary
Activity: 2464
Merit: 2377
July 16, 2020, 08:20:33 AM
#28
In my opinion, we all need to develop a natural immunity against coronavirus but without vaccines, let alone compulsory ones. Weak people have always died and will continue to die and there is no stopping this process. Personally, I don't care what I die from. It's a natural selection and only it can make us stronger.
member
Activity: 868
Merit: 15
July 16, 2020, 06:10:41 AM
#27
The decision to start human testing at an early stage in early July as an antidote to corona is underway but you're right no one knows how much damage it has done. experts say that corona can be prevented without the vaccine but it is more important to be careful. It is safer to stay at home by stopping testing for the virus. In this case, the microorganisms will not be able to nest in our body and this infection will end very soon.
legendary
Activity: 3990
Merit: 1385
July 15, 2020, 05:18:25 PM
#26
Working, safe, test vaccine = baloney. Why, they haven't even taken pure Covid, and infected other people with it, intentionally, to see if the virus is for real! And that is one of the medical requirements to test for a dangerous virus. See Koch's Postulates, and Rivers' revision to them:
Koch:
3. The cultured microorganism should cause disease when introduced into a healthy organism.

...

Rivers:
7. These sequence-based forms of evidence for microbial causation should be reproducible.

Nobody has even tested according to the requirements in the above Wiki link. The whole thing is a big joke. And I don't mean that it isn't a real virus. But I do mean that nobody knows for sure if Covid is what is doing the damage.

Cool
legendary
Activity: 1904
Merit: 1277
July 15, 2020, 12:18:09 PM
#25
There is news emerging from Russia that a covid-19 vaccine being developed in the country has passed the phase of human trial, an excerpt of the news reads thus:
Quote
Elena Smolyarchuk, chief researcher for the Russian Center for Clinical Research on Medications at Sechenov University, told TASS newswire on Sunday that human trials for the vaccine had been completed and those test patients will be discharged soon.

I think UK was way ahead in vaccine game and they have the right kind of partnerships to work efficiently led by huge manufacturer astra zeneca but after starting human trials there has been silence from them or maybe they will update about it after completion of trials. I hope humanity will get out of this trouble soon.

One thing that has become apparent during this pandemic is just how eager a lot of countries are to claim that they are 'world leaders' in fighting it. Probably the closest we have to an impartial source is the Draft landscape of COVID-19 candidate vaccines from the World Health Organisation (today, PDF available from the linked page), which suggests that Sinovac (China) and Oxford/AstraZeneca (UK) are leading the way, and are the only candidates that are currently at Phase 3 of development. Moderna/NIAID are also about to start Phase 3, but haven't done so yet. Specific details of the Phase 3 trials here (Sinovac) and here (AstraZeneca).

Summary and visualisation (from the Guardian) below:



Quote
How are vaccines tested?
In the pre-clinical stage of testing, researchers give the vaccine to animals to see if it triggers an immune response.
In phase 1 of clinical testing, the vaccine is given to a small group of people to determine whether it is safe and to learn more about the immune response it provokes.
In phase 2, the vaccine is given to hundreds of people so scientists can learn more about its safety and correct dosage.
In phase 3, the vaccine is given to thousands of people to confirm its safety – including rare side effects – and effectiveness. These trials involve a control group which is given a placebo.

Sinovac
Chinese company Sinovac is developing a vaccine based on inactivated Covid-19 particles. The vaccine has shown a promising safety profile in the early stages of testing and is now moving into Phase 3 trials in Brazil.
University of Oxford/AstraZeneca
The University of Oxford vaccine is delivered via a chimpanzee virus, called the vaccine vector. The vector contains the genetic code of the protein spikes found on the coronavirus and triggers a strong immune response in the human body. The vaccine is in a combined phase 2/3 trial in the UK and has recently gone into phase 3 trials in South Africa and Brazil.
CanSino Biologics Inc./Beijing Institute of Biotechnology
The vaccine developed by Chinese company CanSino Biologics and the Beijing Institute of Biotechnology – a university close to the Chinese military – reportedly showed promising results in phase 2 testing, although no data from the trial has been published. In a world first, the vaccine has now been approved for military use, but it is unclear how broadly it will be distributed.
Moderna/NIAID
American biotech company Moderna is developing a vaccine candidate using messenger RNA (or mRNA for short) to trick the body into producing viral proteins itself. No mRNA vaccine has ever been approved for an infectious disease, and Moderna has never brought a product to market. But proponents of the vaccine say it could be easier to mass produce than traditional vaccines.


https://www.theguardian.com/world/ng-interactive/2020/jul/15/coronavirus-vaccine-tracker-how-close-are-we-to-a-vaccine

legendary
Activity: 2184
Merit: 1302
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July 15, 2020, 10:02:59 AM
#24
The economic problems have got nothing to do with the virus. The virus is just being used to collapse economies that are no longer viable due to toxic debt.
It prolly means the same thing imo, the virus isn't crumbling the economy directly, it's the measures taken to curtail the spread of the virus that has led to economic collapse; that being said, whichever way it's put, the virus is the causal factor/root cause of the current economic collapse. The US and some other world powers i'm sure have a viable economy, but despite that, their economy has still experienced downturn due to covid-19, though it's the countries with more debts and a poorer economy that has suffered most, but with none left out.
legendary
Activity: 2828
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July 15, 2020, 09:22:41 AM
#23
The economic problems have got nothing to do with the virus. The virus is just being used to collapse economies that are no longer viable due to toxic debt. The currencies are in a similar state. The worst part is that the virus is being used in an attempt to take over human immunity, and to allow the like of Bill Gates to control it. He grew Windows by creating a virus ridden product, and forcing people to purchase "cures" that didn't work, and reduced the efficiency of the computer. Now he is trying to do the same with human life.

Take control of your own health and lifespan, and reject all vaccines.
sr. member
Activity: 1344
Merit: 250
July 15, 2020, 09:03:52 AM
#22
whether it is true if the news is true indeed good news for the whole world I hope the vaccine can be found in the near future to make the problem this virus could be over soon so that everyone could live normally without any problems because the virus every man should experience economic problems and all becomes difficult I hope all is back to normal.
legendary
Activity: 2828
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July 15, 2020, 08:14:11 AM
#21
There is no testing to see how vaccines react with other pharmaceuticals, or the damage they do to various organs in the body. Rhey seem to rely on creating antibodies, and ignore other methods that are used by the immune system. T-cells and mucosal protection for example.

The virus can only live for about 5 minutes on hands that carry protective microbiota, and sanitising destroys this. What we should be doing is to stand in the middle of the room wearing sleeveless shirts, and waving our unsanitised arms to collect the virus, and let the microbiota kill it. I think this would be more effective than stupid monkey face masks that act as virus life extenders.
full member
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July 15, 2020, 05:41:13 AM
#20
As per WHO statement we are not going to find a complete cure for this virus because it keeps mutates so if we found a vaccine which will become innefective before it comes to public market because the virus will change its behaviour and finds own way to survive for the antibodies the vaccine were created for.Its more like a business motive but not going to bring any real change in my opinion.
full member
Activity: 798
Merit: 104
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July 15, 2020, 03:05:03 AM
#19
The country considers it a ‘moral responsibility’ to start out the method of rapid vaccine development to stop coronavirus infection that's why the 2 vaccines that are developed have quickly become human clinical. India wants to usher in vaccines as soon as possible. that's why no effort is being spared Both Indian vaccines are successfully tested in rats and rabbits This information has also been submitted to DCGI Both vaccines were then cleared in early July to start human testing at an early stage Human testing of two Indian vaccines is being started at an early stage this month.
legendary
Activity: 4760
Merit: 1283
July 15, 2020, 01:15:13 AM
#18
The 'flu shot doesn't work, and messes up your immune system. How are they going to create a vaccine for an RNA virus that mutates? Especially as they focus on antibodies, and those are just one of the ways that humans fight these viruses. Nature has spent thousands of years developing and testing safe ways to counter the multitude of viruses that we are exposed to every day, and we should be nurturing that, and not trying to destroy it by funding Bill Gates eugenics programmes.

Here's how:  I've seen 'trial balloons' alluding to the technology for a number of years now, and came close in my mind to guessing the underlying technology they plan to use might work.

You get a 'platform' implanted into your body.  This 'platform' is capable of producing any genetic sequences it is programed to produce.  It is programmable from outside the body either through ultraviolet signaling or wireless.

The RNA (and DNA) vaccines being worked on, and in fact are being tested on people (dark people in underdeveloped countries often) right now work by turning people into a genetically modified organism.  That is to say, the 'vaccine' infects their cells with 'designer' genetic material which programs the cells to make virus parts.  The virus parts your cells created are then attacked by your own immune system to create an immune response and 'immunity.'

The sales pitch for dealing with fast mutating RNA viruses like coronavirus will be that the detection of new viruses via a VERY intensive surveillance network (which 'we' NEED), and the subsequent re-programing of people's 'embedded nano-platforms' will be so rapid turn-around that they can stop all infectious diseases from now forward.

A happy side-effect is that if an individual refuses to take the nano-platform, that's fine.  They die when the next MERS happens to make it's rounds.  And 99% of the population will be happy because 'platform deniers' are putting everyone at risk.

legendary
Activity: 2464
Merit: 2377
July 15, 2020, 12:30:08 AM
#17
The 'flu shot doesn't work, and messes up your immune system. How are they going to create a vaccine for an RNA virus that mutates? ~

I agree. It's almost impossible to create a vaccine against RNA viruses. I read that if scientists get all the strains of this virus, they can determine the same part in each of these strains. Only then will it be possible to counteract the mutations of the coronavirus.
legendary
Activity: 2184
Merit: 1302
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July 14, 2020, 01:18:26 PM
#16
I think this has now become an international business and any country which might successfully develop a vaccine would surely sell it at such prices and make it most advantageous to them. I often see in news everyday like Italy has developed vaccine, Germany developed etc etc, I don't think it's going to be this quick and we shouldn't really trust on any such news for the time.
I also hinted at the commercialization process in the op, if it's possible that a vaccine produced in any country is going to be successful, then it's also a very effective way to make money from it, and this will help their economy to prolly recover faster than others, as you'd imagine, there will be a huge demand for it, and that demand will cost money for it to be supplied all around the world.

Imo, it's not a bad business to say the least, the thing is, just as many users have touched on in this thread, is if a vaccine can be trusted and how many willing people will want to take a shot, not many I'd think.
legendary
Activity: 2828
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July 14, 2020, 12:13:22 PM
#15
The 'flu shot doesn't work, and messes up your immune system. How are they going to create a vaccine for an RNA virus that mutates? Especially as they focus on antibodies, and those are just one of the ways that humans fight these viruses. Nature has spent thousands of years developing and testing safe ways to counter the multitude of viruses that we are exposed to every day, and we should be nurturing that, and not trying to destroy it by funding Bill Gates eugenics programmes.
legendary
Activity: 2464
Merit: 2377
July 14, 2020, 11:12:15 AM
#14
Do you consider that maybe we have sophisticated instruments and equipment these days? The reason why the testing is bit fast. But anyway, it is your prerogative on how you want with this vaccination thing and as you said, you are very familiar with Russian ways on this aspect. And we will see how potent their vaccine will be in the years to come.

No matter how smart the scientists are and how sophisticated the instruments are, we will never be able to outrun time. The main problem preventing the start of mass production of the vaccine is to test it for side effects. But it takes a very long time.
legendary
Activity: 3990
Merit: 1385
July 14, 2020, 09:18:23 AM
#13
Working on and testing a Coronavirus vaccine is like placing the cart a thousand miles ahead of the horse. Why? Because of the scientific/medical rules for testing for a virus.

In 1884, a 4-step process was developed by a couple of doctors, for determining if a disease was what they though it was. This process came to be known as Koch's Postulates. Number 3 in Koch's Postulates is:
The cultured microorganism should cause disease when introduced into a healthy organism.

Over the years, medical people have upgraded Koch's Postulates. In the 21st Century, an upgraded list includes as the last one of seven, a part similar to Koch's 3rd postulate:
These sequence-based forms of evidence for microbial causation should be reproducible.

How do you reproduce the disease as talked about in both lists, above? You reproduce the disease by injecting the virus into another person to see if he develops the disease. Has this been done? Does anybody have evidence that this has been attempted anywhere? This DOESN'T include the idea that someone else in proximity to the sick person, simply gets sick, as well. This is the intentional injecting of the virus into a healthy person to see if it makes him sick.

Has this been documented to have been done anywhere? If it hasn't, basic medical identification of the virus is in question, because accepted medical practices have not been followed.


DO **NOT** GET TESTED FOR COVID-19 IF YOU ARE **NOT** SICK



Many people are being encouraged to "Get Tested" for COVID-19 even if they aren't sick.  Docs are telling people "we just want to make sure."  BAD IDEA.   When you take a COVID-19 test, there is a fifty percent (50%) "Error Rate" in the test.

Turns out, according to the CDC, the present COVID-19 tests might come back "positive" if you've merely had the common cold!   That's right!  Because the "Common cold" is another coronavirus!  Here, Look at this from the CDC Web Site . . .



Here's a direct link to the CDC web site; read it for yourself HERE

So the test results are grossly unreliable.  But it gets worse . . . a LOT worse.

If your test comes back "positive" your name and address immediately goes into a State database shared with Police, Fire and EMS.  So if you call the police for anything . . . like an ambulance . . . a message comes up on the police dispatcher's computer telling them "Universal Precautions Required at this address."    Your so-called "medical privacy" under the HPPA laws . . .  GONE!

Once that message pops up in the police department, every cop, every fireman, every EMS worker in your town immediately knows someone in YOUR HOUSE is infected.  In small town America, the Gossip mill starts immediately.

It gets worse.  In California, the Child Protective Service is filing legal actions against parents who test positive, to TAKE THEIR MINOR CHILDREN AWAY until the parents are no longer positive!


Cool
hero member
Activity: 2002
Merit: 534
July 14, 2020, 06:51:23 AM
#12
I think UK was way ahead in vaccine game and they have the right kind of partnerships to work efficiently led by huge manufacturer astra zeneca but after starting human trials there has been silence from them or maybe they will update about it after completion of trials. I hope humanity will get out of this trouble soon.

That would make sense why they didn't want to partner up with the EU to work on a vaccine program for everybody. Let's see if they can keep up being ahead of everyone else in Europe. UK was hit particular hard during the corona crisis and definitely needs a lot of vaccines for their own population - but being completely egoistic is not alright.
member
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July 14, 2020, 05:28:49 AM
#11
There is news emerging from Russia that a covid-19 vaccine being developed in the country has passed the phase of human trial, an excerpt of the news reads thus:
Quote
Elena Smolyarchuk, chief researcher for the Russian Center for Clinical Research on Medications at Sechenov University, told TASS newswire on Sunday that human trials for the vaccine had been completed and those test patients will be discharged soon.
This news cannot come quicker for countries that are yet to reach their peak and still losing countless numbers of their citizens to corona virus daily. How reliable can this information coming out from Russia be, and if it indeed is true, what does it mean to the world at large and how do you envisage the commercialization process of the vaccine.

Source: https://www.forbes.com/sites/kenrapoza/2020/07/13/russia-completes-human-trials-of-covid-19-vaccine/amp/
I think UK was way ahead in vaccine game and they have the right kind of partnerships to work efficiently led by huge manufacturer astra zeneca but after starting human trials there has been silence from them or maybe they will update about it after completion of trials. I hope humanity will get out of this trouble soon.
full member
Activity: 1022
Merit: 133
July 14, 2020, 04:05:36 AM
#10
I think this has now become an international business and any country which might successfully develop a vaccine would surely sell it at such prices and make it most advantageous to them. I often see in news everyday like Italy has developed vaccine, Germany developed etc etc, I don't think it's going to be this quick and we shouldn't really trust on any such news for the time.
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