The ultimate in pleasure arises from letting go of your desires.
I hope you realize that wanting to experience pleasure is itself a desire. But disregarding your contradiction, what would be the motivation to keep on living if you have no desires?
I do realize, and I said what you're saying in post#36.
If you had no desires, you wouldn't be motivated to live. No desire --> No action as mentioned above. That's why there's no life without desire, or on the other side of the coin, no life without suffering (as the Bhuddists say).
The interesting phenomenon that the less you desire, the more pleasure you are able to receive. For example in meditation, the less you want to experience "states" while you're meditating, the "higher" you are able to get. (Meditation really can result in natural highs).
Contrary to what many people think, it is possible to "control" or influence your desires (and fears) quite extensively.
Can you look at a huge growling dog without feeling fear?
Can you look at a really hot woman without feeling desire? (try it and see what happens)
It's the same sort of mental function.
However letting go of your desires completely is tantamount to relinquishing your consciousness. As long as you're aware, you still have some left.