It's going to be a very difficult match to predict as both teams are rivals at the moment as they're using only one point to pass each other therefore, I think the match is going to be a draw game. If the match doesn't end in a draw then any team that win will have more chance of topping the league for a very long time and having the potential to win the league as it's in matches like this that we sperate the winners from the running up. Napoli lost in their last game against Atalanta but Inter Milan won against Arsenal therefore inter Milan are in a better position to win building on their win against one of the best teams in the premier league. Statistically too, inter Milan has an advantage.
I think here we need to take into account that Napoli had a rest all week, and Inter had a very difficult match with Arsenal. Yes, for them it was a home match, there were no flights to London and back, but in any case it was a difficult game in which Inter players gave a lot of effort. And this will be a home match for Inter again, a very important match because they got very close to Napoli and a win will allow them to return to the top of the table, in fact they will not be satisfied with even a draw, so I think that Inter will not lose.
The match will put at stake the top position of the current Serie A standings, so most likely we will see a match that will run tight and also have high intensity later, Inter Milan may have the advantage of playing at home and high motivation to return to the top of the standings, but the fatigue factor after the UCL match can certainly be a factor that affects their performance later, especially when facing Arsenal they fielded the majority of the main squad in that match.
While Napoli, of course they have more rest time so it allows them to have a squad that is better prepared in terms of performance and also stamina later, so I think both teams might end the match with a draw, although if there is one team that wins of course maybe with a very thin score later.