The first week of Serie A doesn't seem so tough for big clubs. Milan meets Udinese, in this match, AC Milan should be can beat Udinese at least with 1-0. However, Milan also needs to be aware of every movement of Udinese players, considering that in some matches, Udinese are also able to provide resistance and some matches they only give 1 points for Milan.
Roma, Inter and Juventus as well, first week face mid and bottom team, I think 3 points is more easy for them.
Just a good start, so as not to strain too hard, in the style of Serie A.
Whatever, all teams cannot win so easily and there will be those who will lose points already in the first round. By the way, Sassuolo is not always an easy opponent for Juventus, and Udinese has also been taking points from Milan for the last few years, playing in a draw. So the round looks simple, but I think there will be surprises in it too.
The match is difficult to predict, but judging by the opposing team, they are at the bottom even though there will be surprises later, but my prediction is that they can win easily.
Only Juventus against Sassuolo I think will be tough but in the end I will also bet on Juventus.
My prediction is still that the big Italian teams can win in the first match of the season, but after the second and third weekends it will be challenging for them, the top Serie A teams.