I am well aware of how the Martingale works and I only mentioned one satoshi because it is the minimum bet. If you want to get down to it someone could have 10,000 bots winning 1 satoshi at a time with virtually no risk in about 2 hours. Of course they would increase that regularly as needed.
I brought up quarters because if you start at 25 cents you would be wagering a mere $128 bet on the 10th loss. The odds of losing 10 in a row if you set the odds to exactly 50% are 1:1024. On just-dice you could, with a large bankroll, get to the 20th bet before reaching the maximum profit per hand. The odds of losing 20 hands in a row set at 50% are one in a million.
In addition, there are ways to adjust the martingale so that you change the distribution of wins and losses in ways beneficial to you. This is especially true when you can adjust the odds to anything you want, from 0.01% up to 99.9%. I'm not interested in getting into the math involved but go look up how you can effect win distributions with gambling strategies for a good place to start.
You shake all that up and mix in a 1% edge, a lot of major BTC holders that are extremely well versed in mathematics (comes with the territory) and a very forgiving bet spread and it can lead to extensive losses for the "house that can't lose".
Once you start getting to numbers like 1 in a million, where it is more likely you win a small lottery than lose your bet on a gambling site, it's not a giant leap to think someone ballsy enough to sit on 10k or so BTC might decide to give it a shot. If the 1 in a million hits then the casino looks golden, but with those kinds of odds it wouldn't be unusual too far outside of a standard deviation for 10's of millions of iterations to go by without it ever happening. And you have to remember, the person "beating the odds" will be accumulating bankroll all along the way making it even harder to "bust" them.
Edit: And the fact that the 1 in a million hitting wouldn't even bust some of those that have graced the tables of just-dice makes it that much worse. Now you need that 1 in a million to come around on schedule every time and the player to not take his wins and go home. With that kind of betting system one could religiously beat the house for months and months on end and in the world of computers he could do so with a bot.
1 in a million is nothing, it's a certainty it will happen if you start with 1 satoshi and you want to gain 1 BTC, because you need 100 million martingale wins to achieve that. Much bigger loosing streak than loosing 20 in a row is almost a certainty when you chase a whole BTC as a reward.
There's obviously something counter-intuitive about the fact martingale will always loose. But it will, it's a proven fact as long as there's limited maximum bet.