I come to this realization after noticing many use win high multiplier using low amount because they have more chance to spin compared to those betting in high bet amount since it quickly consumed their bankroll.
This is actually a partial truth. If we have $100 with a smaller bet, we will have more spins, but that does not mean that we will hit anything...
With a $0.2 bet we will have 500 spins, it happened to me several times that even after 300 spins I did not get a bonus, some even over 500 spins. And if we catch the bonus round, it is not a guarantee that we will get a high multiplier... we can catch more bonuses, but if they all give a little or nothing, we will end up with a 0 balance in the end.
With $100 I would rather choose to play 100 $1 spins than 500 $0.2 spins... or I would go for a bonus buy, super spins are usually x500, so I would rather buy $100 super spin than $20 normal spin, if there is an option.
Basically, there is no "the most important skill" in slots, we just play and hope for some luck to find us. And sometimes that happens, sometimes not...