You got your wife's life. You have used the money you have to save your wife from the disease so it's fine. If you lost your BTC for nothing or gambling, that would be something else so it's fine. By the way, there are more coins today that you still can invest in. Don't wait for them to go high,
Nah, dude you aren't the biggest crypto loser there is if there is really one because there's Laszlo to compare to you, he got the pizza but the prize was too big to pay with 10k, although there is no regret to him because he knows that he didn't expect that the prices will go this high. I hope that you will find some way to restore hope in you.
Laszlo still has a lot of BTC, I don't think he is the biggest loser. His transaction actually made it a very historical act in BTC that every year there is BTC pizza day to celebrate it. There are users who had lost it all like the ones who lost his hard drive to which thousands of BTC were there inside because that drive was used to store the mined BTC.