I expect them to be more motivated and beat Tottenham at their stadium. It's always nice to see Mourinho - Guardiola clash.
I think Tottenham would come through this time. They have been bullied one too many times in their recent meetings. One thing I've noticed this season is that, Man city might be losing/drawing underdogs but when it comes to playing against big teams (with the exception of mid-decent teams like Leicester city) they always step up their game. They held Liverpool down with a draw just before the international break so I feel they'll give the same treatment to Tottenham.
I'm gunning for a Tottenham win though. Dudes have been real solid this season. They've lost just once this season so they should keep it that way for now.