If you operate your casino without license as it might be in terms of cryptos where the government can't track the transactions to imply you to get licensed but you would not get much response for such a casino. People needs to be secured about the games they play and hence each gambler including me would choose a platform which is licensed and probably fair.
You can consult your CA to get some more legal information about launching a casino in your region. You would also need to set-up a office space where you could store the credentials and you could run the platform from that place. You would need to be centralized if you wish to get licensed and for it you would need to show each and every transaction/bet to the authorized parties in order to get you a license.
Yes ! in every country there will be a law that regulate the gambling in each country, in every business that you will make, you need to apply all the necessary documents so that it would not be a hassle soon,if the government notice your business, once you establish it. Also, players don't want to play in an illegal casino , they might go to jail or lose their fund once the government raids your office where you develop the website.
Don't be complacent. Don't run an online casino without permits, even you are running on cryptocurrencies. Seek advice from local personalities available that are knowledgeable of the risks and pre-requisites of running one in your local state. Also, don't rush things, and make testings to make sure your casino won't be abused and bankrupted by some strategies.
Yes! especially that the mode of payment is crypto in which not all the government are aware and not all of the local governments approves that and they know how does it works, papers must be submitted.