The Europa League has its own level of difficulty because it is play by teams from several leagues, not the same as what they face in the premier league.
If they feel the chances of winning the EPL title will be tough then the same will happen in the Europa League as Manchester United will be competing with the like of Freiburg, Barcelona, Feyenoord, Sociedad and Arsenal.
Europa League is at lower level than Champions League but not all matches in Europa League are easy. There are big clubs and big matches between them in Europa League. Manchester United and Barcelona matches are examples and we can watch more matches like this because many big clubs are playing in Europa League 2022 - 2023.
To win any European league, being strong is not enough, but a winner must have luckiness too.
Sevilla - PSV is going to be one of the challenging matchups in this stage of the Europa League.
This is the first ever meet of these teams with each other. I'm seeing PSV one step ahead truthfully. Because Sevilla have been terrible for a long time period since the beginning of the season. They just defeated Getafe in the La Liga and finally got a win after a long break. I don't know if they can improve their form very much until the first leg here. But it will be a really difficult for them to be completely ready until then. PSV are already one of the decent teams of the tournament. Sevilla are a big threat on paper because of their history here maybe. But realistically, they aren't better than PSV for now.
They are both good clubs and needless to say, Sevilla are a most successful club in Europa League history.
Many people can feel shocked if they know Sevilla have won 6 Europa League trophies in history and all of those trophies come from 2006 to 2020. A next club behind Sevilla in Europa League history is Inter Milan with 3 titles.
If Real Madrid is a king of Champions League, Sevilla is a king of Europa League. PSV will have more stress and pressure when playing against Sevilla.