[I just posted this in the Bitcoin Discussion Forum but I usually hangout here, so forgive me for posting it again here]
After seeing the tragedy unfolding in the Philippines over the last couple of days, I felt the need to donate to a disaster relief charity here in UK (
http://www.dec.org.uk/appeals/philippines-typhoon-appeal).
I was pleasantly surprised that the charity accepts donations via PayPal, which led me to send an email to them to ask whether they had considered accepting BTC too. It then struck me that if a charity were to receive lots of similar requests, they could begin to consider it as a means of receiving donations. After all, charities are pretty hard up these days and are always looking for innovative ways of raising money. BTC seems absolutely perfect for charitable giving/receiving, especially across international borders: no transaction fees = more money straight to the charity.
Then, with my speculative hat on
I figured that if a big name charity were to begin to accept BTC it could generate lots of positive publicity ("Oxfam accepts Bitcoin", etc).
Let us all bombard household name charities with requests for them to accept BTC (obviously, you must be willing to donate something too!).