- We still don't know if Super Covid effect vaccine effectioness.
Modern vaccines target the spike protein of the virus, which docks onto the target receptor (ACE-2 in the case of SARS-CoV-2).
So it's unlikely that vaccines cease to work on mutations.
However, antibody therapy would only work to some extent, because antibodies are way more specific to virus dns, while the spike protein is highly unlikely to change.