I have accessed stakes though VPN and all went smooth. But, their TOS is against multiple accounts (
may not create multiple accounts). So, it would be a problem if they notice that you are using multiple accounts.
AFAIK, crypto-games is more strict about multiple accounts. I have seen lots of gambler's accounts seized/locked for that reason.
Another house which is more strict about multiple accounts is freebitco.in as people try to abuse their easy affiliate program.
My suggestion to you is, try to have 10 accounts and 10 different gambling houses. A problem-free way which may ensure tension-free mindset and I believe a good mindset is more important while you are engaging in developing a strategy. We are all here to know what strategy you are developing with multiple accounts, it is really creating lots of curiosity
.