OMG, Why I didn't saw that myself?
I'm gonna deploy a stable release of Bitcoin Core to factor this out! Thanks!
I've been monitoring my P2Pool Node very closely since the update to the last Bitcoin Core version. I found out with Block #339.597 (which took about 50mins and had more than 2000tx did not grow beyond the the maxblocksize of 1.000.000! This is great news now the P2Pool did not gave any "playload too long" error at console. The update to a later Bitcoin Core did the trick. I would advise everyone to update their Bitcoin Core concerning this issue!
Thanks for the good help and your efforts everyone!!!