The running is the same because they both involved players playing, the same thing but the little difference is the online and offline, onw require you to go to a place where there is gambling and the other one need just any device that can get you and internet.
It's definitely profits, if you are not making much money, it's means that you will be making loss and that means they will be losing much on the profits the casino is expected to make at then end of the month or th year.
I think depends on how large the offline casino is. If the offline casino is large, you will need much number of staffs to manage it together but if it's small, then you need just few people but as for online casino, even if the games are large in number or small in number, you can hire any numbers you think it's okay for the online casino. However, you need to have a web developer to be active if you own online casino.
And the last question is, which one would you go for if you have the resources?
Casino are all diffict to manage and supervise. I think online can only be supervise by a web developer but as for offline casino, you need every staff to be available to monitor your business and every activities.