are payouts for the coin-switching port in each coin it switches to? Unless it is selling the coins right after making them I don't see the point. Example- if FTC is really profitable so it is mined for a day then its value crashes and it switches to LTC. Now I have a bunch of worthless coin and have to wait for it to go back up to how much it was worth when it was being mined to sell. Unless the payout for mining on the coin-switching port is in one currency I don't see how this would work.
There is always a risk that a coin can crash, but generally, coin values are fairly stable day to day. Most of them are certainly stable enough that you can withdraw and cash in your coins or trade them for your currency of choice before the price changes too much.
The largest driving factor for profitability is coin difficulty, which can be quite extreme on some coins. For example, FTC difficulty just dropped 41%. FTC has been trading at .0009-.001 for over a week now, so when the difficulty dropped, the profitability went over LTC's.
In the future I may allow auto-conversion of payouts to a particular coin, but right now if you don't want a coin your best bet is to send it directly to an exchange with auto payout and either go in manually and sell it each day or write a bot to do it. (In fact, if someone were to write an auto-sell bot and share it with the Multipool users, well I think that might even be worthy of Hero membership.)