There can be great harm from taking profits and continuing to pull out value and failing refusing to continue to invest and/or to let your investment ride, especially something like bitcoin... and so you think that you are doing great because you keep pulling out your profits, and then when some guys might be receiving 10x to 50x or more in profits after 5-10 years, you might have ended up pulling out relatively low levels of profits and you are still struggling to build up a sufficient nest egg (or investment portfolio).
You might be suggesting that you are being greedy by taking profits, when instead you are short-sighted and scared and unwilling /unable to let your investment ride, and too busy gambling rather than investing.
You call what you are doing investing, but you are not.. you are gambling. .because you have little to no ability to stay in, and probably you have lack of discipline and/or a lack of a long term plan. .and you end up getting scared at every little profit so then when you get scared, you pull out the measly profits... and yeah, maybe you made some money.. such as 50%. but when you really want to start to live 4-10 years or later down the road, you still are doing the same things and finding the hustle and you have not built up a nest egg.. so you might feel like you are the smartest guy in the room when you are living it up, but if you have to keep working until you are 70 versus the guy who might either be able to stop working early or at least be able to choose the quantity of his work, then you might feel that you either had not been stocking away enough profits and./or you were holding your profits in the wrong assets, currencies and/or properties.
I explained the trade offs, so in the end it is up to you to figure out the trade offs and how you want to play it.
In other words, Make your choice. It's up to you.
You can do whatever you like when it comes to how to manage your investment, including whether you pull out amounts at various points or if you cash it all out.
Yes, taking out all your profits is problematic, and like I also mentioned taking out most of your profits can be problematic too, especially in terms of causing the compounding to count for less.. and so you can figure out your own calculations based on your own circumstances in terms of how much of your BTC you want to continue to let ride.. and wether you might have had been better to NOT take profits rather than always being concerned about taking profits, which means selling too much too soon.
Sometimes people do come to the end of their lives where they might start to dip into principle, which also could be a problem if they miscalculate.
Another thing is that they could experience some unexpected emergency(ies) that they believe to justify them in terms of taking from their bitcoin rather than any other sources (in the event that they might have other sources in which they could draw upon). We should try to design our investment into BTC so that these kinds of situation would not come up, but designing around it may or may not be possible.