1 - keeping your private keys private
2 - ensuring your full node continues to act in ways as intended
3 - ensuring your miners mine at the pools as intended
There is also a potential fourth regarding clipboard, and display malware.
Issues regarding 1 belongs in the wallets sub, 2 belongs in dev and tech, and 3 belongs in the mining sub.
I don't think there is a high enough volume of these types of threads to warrant a new sub.