It's pretty safe to conclude that investing is risky. Even if you choose to go with the safest-looking options, the risk is always there.
Also, I'll have to disagree with the OP's statement regarding 10x capabilities by investing in Bitcoin or Ethereum. Nowadays, in order to achieve a 10x from Bitcoin, it'd have to surpass $200.000, which is highly unlikely to happen anytime soon.
to reduce such risk, even if you are investing in top alts, you should also keep up with their updates and not be contented for months or years without checking the progress of the coin. there are some instances like the xrp lawsuit and the terra crash. if you think there is surrounding news towards the coin you are holding, better keep an eye on them and decide which path you will take before you totally lost your investments.
The only one I feel comfortable doing is with Bitcoin, which has proved its worth throughout the years. Apart from Ethereum, perhaps, I don't think I'd hold any other altcoin without paying attention to the market. Cryptocurrencies are not autopilot, they need persistence, patience and strength in order to survive and earn money through them.