There is a really interesting statistics about this matchup. I checked the head-to-head games and saw that Milan can't defeat Napoli in San Siro in a league game since December 2014. Napoli will have a huge psychological predominance against them as a result. It is up to Milan to put an end to this bad luck. They have a Champions League game to start in ten minutes and getting a win here would motivate them even more for the Napoli game. Milan and Napoli are both doing great in the Serie A now. Maybe it is a risk to take but I'm thinking of betting on Milan win @2.24.
Since Napoli is still in a solid ground in this season, showed that Milan can't defeat them in their next match because Napoli has a potential squads that know how to achieve goals that will bring victory at the end of the match. Napoli will win Milan 2-0 to prove to their fans that they have what it takes to defeat any strong teams in this season. I don't think, Milan can make this match draw because Napoli strikers are well organized to use their new strategies to score many goals from this match that will make people to believed that they remain among the best strikers in this tournament.