Why not? I'm not saying the board design should prioritize price over quality, but there's also no point in spending more money than what is needed. 10 cents saved on a $150 purchase has the same value as 10 cents saved on a $1 purchase.
Your time would be much better served trying to buy BTC cheap then, since it's the majority of the cost.
what i mean is it's not worth trying to penny pinch, time is the #1 most important factor here, I would say design a PCB Assembly that you know will work (over engineer it where possible) and test it as throughally as possible prior to the actual chips arriving
This being said, I have seen QFN-48 clamshell chip carriers around with thick gold plated slugs for the center pad. Since Avalon sample chips are coming earlier than the full batches, would it be helpful to make a, say, 2- or 4-avalon board with all the necessary hardware (interface uC, smaller version of power supply) to test/debug software on? I'd imagine you could get at least 20-30 seconds of full speed hashing before thermal issues arose (whereas with an unmounted chip I wouldn't trust it hashing for more than 2-3 seconds). That way you could finalize your design with higher confidence, and possibly have near-complete boards ready and waiting when the full Avalon batches show up.
http://www.mouser.com/ProductDetail/3M-Electronic-Solutions-Division/288-4205-01/?qs=sGAEpiMZZMsF5fZXKZXt6HnXba9GH55j3eF08QDY59M%3d
It'd probably cost you about $1000 to develop this prototype/debug platform.
I'd be willing to lead the PCB design on this. My code writing is kinda weak, but how hard could it be to pass some data from usb/cgminer to I2C/SPI/UART? Anyway, I'm sure someone like BKKcoins would be willing to help =)