Yes, MultiMiner 2.0 requires bfgminer 3.7 or higher. It is not compatible with earlier versions.
You can already add whatever coins you like. You do not have to pick one from the drop down when adding a configuration.
I am not sure what you mean by custom profitability - wouldn't that change all the time?
It uses the --quota argument in bfgminer so that 1% of your work goes towards one of my pools. No extra steps needed by you.
Because bfgminer and cgminer now use incompatible methods of listing available devices and I do not have the time or resources to keep MultiMiner compatible with both. Anyone is free to start contributing anytime. You can read more about the decision here:
https://bitcointalksearch.org/topic/m.3646762