Did you actually consider changing from Scrypt to something which can not be mined by ASIC's? I think as soon as the ASIC hit mainstream a lot of the current scrypt coins will lose all it's value? I'm talking about those 60MH miners not small gridseeds.
It's tough to know what the effect will be, but litecoin will most likely be the coin that get hits hard with Asics initially. Since there is enough volume to support people dumping out. On the other end of the scale people buying gridseeds have big money, esp the ones from KnC that cost close to $10000. Now if it's someone that has dipped into there life savings and needs to ROI then they will be dumping out which could initially effect coin prices or make it so it costs more to mine the coin with the price/hash ratio. The later would only be a problem though if all POW scrypt coins became unprofitable to mine cause a person mining to ROI is going to take the best current priced coin and mine it via multipools.
On the other end of the spectrum you will have a rich investor who will buy some hw and also mine a coin they supporting not to dump out but to use and even buy more up. This is why POW coins with no USE will die out with ASICS and the rest will carry on.
Changing to a different ALGO means you are supporting people who can only afford graphic cards.
The above is just my opinions of course and could be totally off.
Future ASICs, including the upcoming KNCs, will support current algorithms. You're not going to get away from ASICs with an algorithm change. You're only going to alienate the people with current generation ASICs, myself included.
The reality is that ASICs are cheaper than GPUs now. A R9 270 will get 450kh at about $120-150 slightly used, and it runs at about 180W. A gridseed 5-chip unit will get 360-500(OC'd)kh at about $100 new, and it runs at 8W. There's a reason people are selling off all of their GPUs right now, and GPU prices are tanking.
-Fuse