In my opinion, their current ranking could not even be said to be safe, because the point difference is not that far they could be overtaken by Arsenal or Liverpool. However, with Liverpool's next match which will be against Atalanta, I am not sure that Liverpool can win, because in their previous match they lost badly, from there I think Liverpool will be less confident in the next match.
Manchester City is currently very happy because the other teams like Liverpool and Arsenal can't get good results and the bad results from these two teams gave Manchester City the chance to have a better situation in the Premier League. In fact, Guardiola didn't start the season well but time after time and especially after the key and effective player De Bruyne got back into good form.
Maybe just like last season see Guardiola and his team win the Premier League at the end of the season even after the bad start they had. But the mistake from the other teams gave them a good chance.
and with Liverpool also having points that are not much different from Manchester City, they have the opportunity to overtake their ranking. with their last two matches they experienced consecutive defeats, against Atalanta they lost badly, and against Crystal Palace they also lost, in their next match which will face Atalanta in the second leg I doubt they can turn things around, but no one knows for sure What will Liverpool's next match be like, whether they will lose again or can turn things around so they can overtake Manchester City's ranking.