It is true that currently Chelsea is difficult to predict because their performance is very unstable, especially when playing away from home. However, when Chelsea is the host, Chelsea wins and draws more, which I don't think Chelsea will let Fulham win at Stamford Bridge.
And head to head both Chelsea teams are superior to Fulham and Chelsea won three wins, one draw and also one defeat against Fulham. And I think Pochettino will plan and give his best in front of his supporters and will field his best squad to win this match, even though every Chelsea match is always in doubt, but for this match I think they can win it.
Of their last ten home games, Chelsea have lost four games and drawn another, meaning their record at home is not that good. But as for Fulham away, their results are even worse, so I think that Chelsea will not lose this match, but I also cannot say that Chelsea will be able to easily win this match. Teams from the middle of the standings will play, with poor defense, so the match will be equal.
Chelsea performance statistics this season cannot be completely trusted even when they play at Stamford Bridge. This means that there is an opportunity for Fulham to gain full points like they did last week against Arsenal. Pochettino must mentally prepare his squad to be able to beat Fulham in order to get closer to the Europa League zone.
I tend to think this match will end in a draw, because the Blues are still facing a storm of player injuries. No less than 10 players are injured, of course this affects their chances of securing full points, and it is quite surprising that Fulham also has the opportunity to do so.
Since taking charge of the Blues, Pochettino has still struggled with player injuries, he has never had a complete squad. Their chances are actually quite big to consistently appear in the EPL this season, because they don't have a match schedule in European competitions which adds pressure to them, unfortunately they failed to make good use of this.