No, in short, don't waste time with many multis with low odds. Just pick one good team with possibility to win even tho they are not the favorite. Or bet against the big favorite because everyone, including Djokovic, Alcaraz, Barca, Real, Bayern, City will lose some point.
Less headache and win once, cover 5 losers. Unlike shitty small odd bets lose once, you need to win 3 times to cover.
If you pick strong teams for a long time, you will have positive net win, but gamblers don't have this style. They want to move from club to club, and sometimes bet on big and strong clubs and other times bet on weak clubs. This causes them more unstable bet results and loss becomes bigger than the first method.
I know odds of big clubs in matches are important too but if you feel unsafe, just don't bet. When you feel safe, bet with strong clubs, and if you do it like 100 times, your bet net results will not too bad.
Like in tennis, chances for losing to Djokovic, Alcaraz in a long term bet is very low but if you bet big in one of their matches, you can lose big.