On that video, what happened was that a dude from South Africa was gambling on a casino site known as Betway. The guy staked ZAR 277.08, and when he started the round, he got about 4,870.24x multiplier, which doubled his staked amount up to ZAR 73,059, which is about $3,900+. he lost the money because he was unable to cash out before he crashed.
In my neighborhood, there is something we call "village people", what we see as the cause for every misfortune. I guess it was the village people that remembered this guy and they got him through his phone. I don't know if we can call it bad luck or not but such incidence is seriously demoralizing. I just hope the guy will not contemplate suicide because I have seen many cases of gamblers doing that when they miss big opportunity.
In my case, I have not actually experienced any situation like that, apart from the usual disappointment you will experience with a club after you place a bet on them, believing so firmly that nothing will stop that club from winning, but they end up losing.
I have had terrible experiences with gambling as well but not like this very one. Notable among them is having my sports bet destroyed by the last match on several occasions. In looking for solution, I started combining only matches that are playing the same time, although this did not solve the problem completely. So misfortune seem to be a normal thing with gambling and everyone must have a taste of his own.