only problem is that these are 3GBit SAS-Expanders inside, most of which only support 2 TB SATA-targets.
That would limit you to 16x2TB=32 TB (29,1 TiB) per enclosure, tying you to the (price wise) unattractive 2 TB disks.
One other thing to remember is that you need to read 1/4096 of the capacity per block. And you want that to finish in less than 240 seconds, as most of the blocks finish much earlier than 240 seconds. So, to mine one fully populated enclosure you'd have to read 29,1 TiB/4096/120 seconds = 64 MiB/sec.
On my 3,2 GHz Box a single (linux-, java-based) Miner thread read in about 14,5 MiB/s, so you'd need 4 cores per enclosure.
But if you have lots of older disks "lying around", this is a very cheap way to connect them.
Just my 2ct.