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Topic: Anyone following the ebola outbreak? - page 10. (Read 39823 times)

legendary
Activity: 3108
Merit: 1359
October 15, 2014, 05:11:05 AM
http://rt.com/news/195536-ebola-russia-vaccine-send/

Vaccine efficiency is 70-90%.

Quote
The vaccine has so far proved efficient against various hemorrhagic fevers, including the Marburg virus which is very similar to Ebola.

Article says that Triazoverin is based on combined mix of attenuated strains of ebolavirus and marburgvirus. So this vaccine couldn't be used to protect immunocompromised people (e.g. HIV infected individuals).

So is it so that the Triazoverin has 70-90% efficiency against various hemorrhagic fevers but has not even tested against Ebola yet?
And the other vaccines based on a strain of Ebola should come out in the next six months?
According to original video they have said that successful experiments were performed with ebolavirus also, but used strains aren't actual nowadays. Samples of new strain already were received but technology requires 1-2 months for breeding the sufficient amount of attenuated version of this actual strain. Using actual strain is required to make sure that vaccine will provide sufficient protection in this outbreak.
Vod
legendary
Activity: 3668
Merit: 3010
Licking my boob since 1970
October 15, 2014, 12:06:43 AM
The BEST way to protect yourself is to break your habit of touching your own face every few seconds.

Edit:  http://www.answers.com/Q/How_many_times_does_a_person_touch_their_face_daily
legendary
Activity: 1204
Merit: 1002
Gresham's Lawyer
October 14, 2014, 11:44:46 PM
Your scenario scares the pants off people who may have to respond. Remember the doomsday cult in Tokyo? Those are the guys who tried killing everyone on the subway system with ricin poison. Imagine if they had serious germs. Some group like that could infect themselves and head out into the crowds. It might be very hard to stop them.
Good point, I should stop, because responding with no pants makes things harder!


Yes.  These people carry another kind of virus, a philosophical one.  When the two combine it's gets messy.


Believe me when I tell you, the folks who "respond" have war-gamed this extensively for decades.  This isn't new to "them". 
Here's a drill on it I remember from a decade ago:
http://www.washingtonpost.com/wp-dyn/articles/A10746-2005Jan14.html

Normal precautions during flu season are good, but stepping it up a notch or two this year might be good.
legendary
Activity: 3066
Merit: 1147
The revolution will be monetized!
October 14, 2014, 03:23:18 PM
Ebola is not a candidate for weaponization. The closest attempt was by the Soviets. They weaponized the related Marburg virus, which also causes hemorrhagic fever. I don't think they ever used it.

But no nation is going to use a wild form of a virus. It would be like shooting a gun with barrels in all directions. You could not control who it infects, nor could you stop it once it starts spreading. In the future there will likely be highly selective germs created that target a particular race for example. Those will be dangerous bugs indeed.

Yes, the future is going to be weird...

But these guys don't need technology, and they aren't nation states.
You know they used to catapult diseased animals and dead people over castle walls?
They aren't interested in stopping the spread of it either.  God will sort it out.
There are a lot of crazies out there.


There is a lot of current effort into controlling the reservoir of infection, which is good because it is uncontrolled currently.  Awareness is the best defense.

Your scenario scares the pants off people who may have to respond. Remember the doomsday cult in Tokyo? Those are the guys who tried killing everyone on the subway system with ricin poison. Imagine if they had serious germs. Some group like that could infect themselves and head out into the crowds. It might be very hard to stop them.
legendary
Activity: 1204
Merit: 1002
Gresham's Lawyer
October 14, 2014, 02:42:09 PM
Ebola is not a candidate for weaponization. The closest attempt was by the Soviets. They weaponized the related Marburg virus, which also causes hemorrhagic fever. I don't think they ever used it.

But no nation is going to use a wild form of a virus. It would be like shooting a gun with barrels in all directions. You could not control who it infects, nor could you stop it once it starts spreading. In the future there will likely be highly selective germs created that target a particular race for example. Those will be dangerous bugs indeed.

Yes, the future is going to be weird...

But these guys don't need technology, and they aren't nation states.
You know they used to catapult diseased animals and dead people over castle walls?
They aren't interested in stopping the spread of it either.  God will sort it out.
There are a lot of crazies out there.


There is a lot of current effort into controlling the reservoir of infection, which is good because it is uncontrolled currently.  Awareness is the best defense.
donator
Activity: 1218
Merit: 1015
October 14, 2014, 01:48:59 PM
Actually such a thread's posts should be kept under national security surveillance. IMHO, I think you dudes are going a bit too far here.

Just my 2 satoshi.

Hey, man. If a terrorist blows himself up at a mosh pit or shopping center, now at least a few people in the US are going to be bugging the Hell out of CDC, FBI, and local police numbers to offer up a completely left-field explanation. The FBI's full of batshit crazies -- I'm sure they'd listen to me. Savin' lives every day -- it's hard work. Cool
legendary
Activity: 3066
Merit: 1147
The revolution will be monetized!
October 14, 2014, 01:37:00 PM
Ebola is not a candidate for weaponization. The closest attempt was by the Soviets. They weaponized the related Marburg virus, which also causes hemorrhagic fever. I don't think they ever used it.

But no nation is going to use a wild form of a virus. It would be like shooting a gun with barrels in all directions. You could not control who it infects, nor could you stop it once it starts spreading. In the future there will likely be highly selective germs created that target a particular race for example. Those will be dangerous bugs indeed.
hero member
Activity: 722
Merit: 500
October 14, 2014, 11:25:43 AM
However I must admit I don't trust GSK, Pfizer and so on...


How about Baxter? Didn't they try distributing vaccines by blowing them up on a train?

edit.

Oh look!

"Newly appointed UN Ebola Czar, David Nabarro, has warned of an explosion of Ebola cases.

http://www.ad-hoc-news.de/afrika-behoerden-bekommen-ebola-epidemie-nicht-unter–/de/News/38397097

Nabarro, a UKIP politician, was the senior UN system Co-ordinator for Avian and Human Influenza when WHO supplied the bird flu virus which contaminated 72 kilos of seasonal flu in Baxter’s biosecurity 3 facilities in Austria in 2009."
legendary
Activity: 1512
Merit: 1000
October 14, 2014, 11:19:27 AM
It's never the same, but simple in general. Attenuation process is based on breeding the virus on the culture of cells which is very different from cells of the natural host. The most difficult part of the job is to find an optimal culture of host cells for replication of virus. In case of influenza virus an optimal breeding host cells culture is an embryo of bird, for example. After thousands of thousands of breeding cycles the viral genome successfully adapts to the new host, but the result of adaptation is lesser infectivity for the cells of an original host. How much lesser? It depends on the virus' ability to mutate. If viral genome is stable then attenuated strain is unable to cause any symptoms of the disease. In case of polio attenuated strain is absolutely harmless while in case of variola, herpes, influenza or measles an attenuated strain is able to cause some symptoms of the disease.

I know how the attenuation process working, but I also know the phenomenon called virus interference between related viruses, possible secondary mutations and the effects of improper vaccine handling.
Please don't misunderstand me I trust Russian stuff. If it's not dead on arrive then it will work for generations, I just don't want to be in the first wave to be vaccinated Smiley. However I must admit I don't trust GSK, Pfizer and so on...
legendary
Activity: 1204
Merit: 1002
Gresham's Lawyer
October 14, 2014, 09:29:29 AM
Actually such a thread's posts should be kept under national security surveillance. IMHO, I think you dudes are going a bit too far here.

Just my 2 satoshi.


No surveillance is needed.  We may be swirling around in one of the internet's weirder backwaters, but this is a post on the public internet, right?
http://www.news.com.au/world/middle-east/islamic-state-jihadists-may-infect-themselves-to-spread-ebola-in-the-west/story-fnh81ifq-1227085919151

Unlike paper money, you can't get ebola from receiving bitcoin transactions over the internet.
legendary
Activity: 1512
Merit: 1000
October 14, 2014, 09:14:01 AM
Have you ever heard of lonewolf terrorists? Their success is fear..you don't need to up the body count if you can instill fear aka terror in people minds. A lot of people in many countries got vaccinated since consequences of not being vaccinated are usually worst. A lot of people in critical occupations (doctors, paramedics, police and military officers, etc.) are being given shots for a whole range of diseases since long time. Here in Italy, I've been given mandatory flu vaccination (as a volunteer paramedic) since the beginning of the SARS scare. No one got untested and probably harmful crap. Probably because no one would turn up to work if they didn't test the shots before.  Grin

Lonewolf terrorists can't do too much harm, as they have limited resources and do not have any meaningful logistic background.

I know mandatory vaccinations, in the army we've got vaccines before we went to some sort of remote shitholes. (The tropical mix was especially fine. We were sick for weeks after that.) However that was some well tested, proven good stuff. With known side effects and time tested protocols.
Please read the news. These brand sparkin' new ebola vaccines are on the way to be pushed through without extensive clinical testing, because of the health emergency. Are you wanna be a guinea pig?


legendary
Activity: 3108
Merit: 1359
October 14, 2014, 09:10:41 AM
If those guys doing similarly good job with a live ebola virus cocktail
It's never the same, but simple in general. Attenuation process is based on breeding the virus on the culture of cells which is very different from cells of natural host. The most difficult part of the job is to find an optimal culture of host cells for replication of virus. In case of influenza virus an optimal breeding host cells culture is an embryo of bird, for example. After thousands of thousands of breeding cycles the viral genome successfully adapts to the new host, but the result of adaptation is lesser infectivity for original host cells. How much lesser? It depends on the virus' ability to mutate. If viral genome is stable then attenuated strain is unable to cause any symptoms of the disease. In case of polio attenuated strain is absolutely harmless while in case of variola, herpes, influenza or measles an attenuated strain is able to cause some symptoms of the disease.

probably going to Liberia grabbing a couple big bottles of booze and having sex with a local prostitute who's already sick with ebola is a better option... or at least a more pleasant and exotic way to die Smiley.
Hm... Seriously, I don't think that you would prefer to eat shit of sick person instead of getting alive polio vaccine.

P.S. Giving that genomes of ebolavirus and marburgvirus family species are very stable, it's unlikely that attenuated virus will be able to cause any symptoms of the desease. It should be pretty similar to polio vaccine in terms of virulence, i.e. a few weeks of asymptomatic carriership and you've got an immunity.
legendary
Activity: 1512
Merit: 1000
October 14, 2014, 09:04:47 AM
To be honest I have some distrust towards live attenuated virus jabs since this summer, as seven of our kittens felt ill with cat flu after the cat flu vaccination. (Feligen RCP is also a live virus vaccine.)
It seems that you haven't seen how the wild strains of Calicivirus are affecting the kittens. And I bet you won't want to see. Roll Eyes


Actually I've seen that on feral cats and on rescued kittens. And you are right I didn't wanted to see again. It was two weeks of night and day hard work for the entire family to nurse all of them back to life.
legendary
Activity: 3108
Merit: 1359
October 14, 2014, 08:50:47 AM
To be honest I have some distrust towards live attenuated virus jabs since this summer, as seven of our kittens felt ill with cat flu after the cat flu vaccination. (Feligen RCP is also a live virus vaccine.)
It seems that you haven't seen how the wild strains of Calicivirus are affecting the kittens. And I bet you won't want to see. Roll Eyes
sr. member
Activity: 322
Merit: 250
https://dadice.com | Click my signature to join!
October 14, 2014, 08:44:32 AM

I cannot imagine how you alone could prevent a similar terrorist attack...other than avoiding the shopping centers (or any other terrorist target). So far the best way is stopping providing ideas to terrorist. If you would prepare yourself for an ebola outbreak other solution are at hand: http://www.washingtonpost.com/news/morning-mix/wp/2014/10/06/how-survivalists-in-america-are-plannning-their-escape-from-ebola-apocalypse-right-now/?tid=trending_strip_4.
I think their shopping list could be useful enough.

Terrorist probably already have their own plans/ideas and I would be surprised to find that they are reading forums like this. However I still doubt the viability of such an attack in our environment with our hygienic standards. To be honest I'm more concerned because of the big pharma companies, as they can use such an opportunity to persuade governments about mandatory vaccinations so they can push their untested and probably harmful crap to us.

Have you ever heard of lonewolf terrorists? Their success is fear..you don't need to up the body count if you can instill fear aka terror in people minds. A lot of people in many countries got vaccinated since consequences of not being vaccinated are usually worst. A lot of people in critical occupations (doctors, paramedics, police and military officers, etc.) are being given shots for a whole range of diseases since long time. Here in Italy, I've been given mandatory flu vaccination (as a volunteer paramedic) since the beginning of the SARS scare. No one got untested and probably harmful crap. Probably because no one would turn up to work if they didn't test the shots before.  Grin
legendary
Activity: 1512
Merit: 1000
October 14, 2014, 08:42:45 AM
Mandatory vaccinations is the most effective policy. However, it's a shame that modern pharma industries prefer to work on the genetically engineered stuff instead of trying to develop alive attenuated vaccines without introduction of artificial changes into viral genome. Just see ebola for example... Only one proposed vaccine is based on a live attenuated strain of the virus. Remaining candidates are the result of genetic engineering. I don't try to say that genetic engineering is evil but it's relatively new technology. Of course the genetic engineering could be used when old approach doesn't work but why don't use the technique which is proven to be effective and safe in 18th century? Seems strange for me.

To be honest I have some distrust towards live attenuated virus jabs since this summer, as seven of our kittens felt ill with cat flu after the cat flu vaccination. (Feligen RCP is also a live virus vaccine.) If those guys doing similarly good job with a live ebola virus cocktail then probably going to Liberia grabbing some large doses of booze and having sex with local prostitutes whom are already sick with ebola is a better option... or at least a more pleasant and exotic way to die Smiley.
legendary
Activity: 3108
Merit: 1359
October 14, 2014, 08:32:23 AM

I cannot imagine how you alone could prevent a similar terrorist attack...other than avoiding the shopping centers (or any other terrorist target). So far the best way is stopping providing ideas to terrorist. If you would prepare yourself for an ebola outbreak other solution are at hand: http://www.washingtonpost.com/news/morning-mix/wp/2014/10/06/how-survivalists-in-america-are-plannning-their-escape-from-ebola-apocalypse-right-now/?tid=trending_strip_4.
I think their shopping list could be useful enough.

Terrorist probably already have their own plans/ideas and I would be surprised to find that they are reading forums like this. However I still doubt the viability of such an attack in our environment with our hygienic standards. To be honest I'm more concerned because of the big pharma companies, as they can use such an opportunity to persuade governments about mandatory vaccinations so they can push their untested and probably harmful crap to us.
Mandatory vaccinations is the most effective policy. However, it's a shame that modern pharma industries prefer to work on the genetically engineered stuff instead of trying to develop alive attenuated vaccines without introduction of artificial changes into viral genome. Just see ebola for example... Only one proposed vaccine is based on a live attenuated strain of the virus. Remaining candidates are the result of genetic engineering. I don't try to say that genetic engineering is evil but it's relatively new technology. Of course the genetic engineering could be used when old approach doesn't work but why don't use the technique which is proven to be effective and safe in 18th century? Seems strange for me.
legendary
Activity: 1512
Merit: 1000
October 14, 2014, 07:55:58 AM

I cannot imagine how you alone could prevent a similar terrorist attack...other than avoiding the shopping centers (or any other terrorist target). So far the best way is stopping providing ideas to terrorist. If you would prepare yourself for an ebola outbreak other solution are at hand: http://www.washingtonpost.com/news/morning-mix/wp/2014/10/06/how-survivalists-in-america-are-plannning-their-escape-from-ebola-apocalypse-right-now/?tid=trending_strip_4.
I think their shopping list could be useful enough.

Terrorist probably already have their own plans/ideas and I would be surprised to find that they are reading forums like this. However I still doubt the viability of such an attack in our environment with our hygienic standards. To be honest I'm more concerned because of the big pharma companies, as they can use such an opportunity to persuade governments about mandatory vaccinations so they can push their untested and probably harmful crap to us.
full member
Activity: 182
Merit: 123
"PLEASE SCULPT YOUR SHIT BEFORE THROWING. Thank U"
October 14, 2014, 07:51:34 AM
So far the best way is stopping providing ideas to terrorist.

This is an interesting idea. Why do you think it's more efficient to prevent terrorist acts by refraining from discourses about potential threats than by sharing potential scenarios and finding the appropriate counter measures? By exposing the problems or risks publicly do you think it increases their potential of realization or do you reduce it by the awareness of the People? And in the case of an event do you think it increases the potential damage or the contrary?
sr. member
Activity: 322
Merit: 250
https://dadice.com | Click my signature to join!
October 14, 2014, 07:22:14 AM
Actually such a thread's posts should be kept under national security surveillance. IMHO, I think you dudes are going a bit too far here.

Just my 2 satoshi.


Well, you are right, but if I don't evaluate all the possible issues I could suddenly find myself on a Baggies-Wolves match, or even worse in a shopping center with my wife right before Christmas and only God knows what could happen to me there Smiley.

I cannot imagine how you alone could prevent a similar terrorist attack...other than avoiding the shopping centers (or any other terrorist target). So far the best way is stopping providing ideas to terrorist. If you would prepare yourself for an ebola outbreak other solution are at hand: http://www.washingtonpost.com/news/morning-mix/wp/2014/10/06/how-survivalists-in-america-are-plannning-their-escape-from-ebola-apocalypse-right-now/?tid=trending_strip_4.
I think their shopping list could be useful enough.
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