Claymore would need to rebuild/load the DAG database anyway when switching from one Ethash coin to another Ethash coin. That is the most time consuming part of the Eth miner startup. Already Claymore is pretty fast compared to others. One thing that might work is if the Claymore miner could be paused. NiceHash does this with their Ethash miner so it doesn't have to rebuild DAG if it goes from Ethash to other coin and back to Ethash.
If you could pause Claymore then you could run two instances pause and switch between them and also start other miner if better profit. That would probably use a lot of RAM/virtual mem though and require Claymore to make some changes to his miner to support it. Might overly complicate the way the node runs and monitors.