Obviously, there's a long road to get there. nLockTime is currently not fully supported by the network. AFAIK BitcoinJS doesn't do multisig, and I know no other javascript client that could be easily embedded in a browser. I don't know if OT currently supports multisignature either, nor if there is a javascript OT client. Being honest, multisig isn't really essential. But multisig may also protect the user against a malware in their own computer. I find this important.
There's still an important trust issue that remains unsolved: the asset issuers. Established companies might not dare openly selling their shares in a black market. Actually, I wonder if any non-anonymous company would. And as we know already, trusting an anonymous issuer is a serious issue. There might be ways to overcome this problem too, but it won't be simple.
You can't trust an anonymous issuer, never ever. Somebody might say he needs some money to expand his mining farm and in reality the money goes to the Mafia. They can make up any bullshit that somebody might believe and there's no way to verify it. They might pay interest every week and even if you don't lose any money there's every likelihood that your money will be used for some nefarious purpose instead of what they told you. No thanks.
Thats why you shouldnt invest in projects that you dont trust fully. But people do. Look at the hyip-world. How many new hyips are bord each week? And really everytime there are people investing to check out if they are valid. They fully know they arent valid but they hope it again and again.
I wouldnt invest from the start. Thats first point. So you can watch the thing a bit how it goes. Then you check if the businessplan sounds correct or not sufficiently explained, if the numbers add up and so on. And then you check what character the issuer shows. Of course he can be a master in his field but a risk remains everytime.
And if the mafia goes into to gain 40.000usd or somewhat? I dont believe that. If such thing earns 400.000 or 4.000.000 then maybe... but then this must be a project sounding fully fine without doubts coming up somewhere and with the possibility to fuel peoples greed. Its not so easy i think to make the mafia pleased with this.
I think mafia will be more interested into the possibility of moving money with bitcoins. Thats probably more matching to them.