In fact, every single comparison I've done between NiceHash and a multi-algo, auto-switching pool - always using NemosMiner - has ended with NiceHash winning. As a result, I've concluded that it's just not worth trying to beat NiceHash at its own game. YMMV, etc. and so on.
I have been away from NH for quite a while now (last year when I compared ZPOOL was ahead of NH for me) -- but I fired it up on two workers to size it up again.
Early impression is that the profit seems quite high right now on NiceHash -- probably due to the "bull market" run we are having (e.g. people willing to pay above market for the power).
Believe me, after all the trash talking I've done about NiceHash (aka NiceHack), no one was more surprised as each and every multi-algo pool I've tested over the last month has come in 2nd place, and often by a startling amount. HashRefinery and Zergpool both brought in 30% less over their 1 week test period than NH. Granted, both pools happened to get on the wrong side of some hard-forks, but since that isn't something you have to worry about with NH I can't really toss out the comparisons as invalid. Both MiningPoolHub and Zpool came in around 10% less than NH over their test periods (1 week for MPH, only 3 days for Zpool) and given the limitations of my test setup I am inclined to call these a tie, but that's rather missing the point: the whole idea behind multi-algo, auto-switching pools is to beat single-coin mining AND NiceHash over time (if you are the type that either cashes out in fiat on a regular basis or just wants to accumulate BTC without buying a shitty ASIC).
And especially since NH is rather restricted in the algos it offers I am even more surprised at the poor showing of these multi-algo pools, but maybe it's not the pool's fault, maybe it's NemosMiner's, so I am contemplating trying another multi-algo miner manager next.
Consider how is it possible (beyond consistent luck +/- getting the best of fluctuating exchange rates) that a pool can consistently out earn the calculated amount at whattomine when WTM considers net hash rate of the entire algorithm across all pools. Also consider that WTM and other calculators are likely ideal earnings; multi algorithm pools often use PPLNS or some PPLNS hybrid which doesn't favor algorithm switching as compared to PPS of nicehash. In other words, what you see is typically what you get with nicehash compared to the ideal earnings on WTM.
If WTM has nicehash near 90% of the top algorithms it's going to be tough to beat especially if hopping from algorithm to algorithm on a multi-algo pool. For example, x17 is the top algorithm on ahash pool and the listed estimates don't even come close to nicehash's rates.
I've gone back to single pool mining vs nicehash.
Plus Nicehack can operate at a loss until they need some more funds to continue then organise a convenient wallet hack…