I don't care if the coin is a MEME or any other if i am to gamble it on a casino. Gambling is altogether a different thing than trading. For trader, you need to know if this is a MEME coin and risk involved with the coins.
Suitable and reasonable, maybe we often stake meme coins like SLP, but not for trading just for placing bets.
If we talk about meme coin PEPE, I think it's meme not suitable for trading, even though they say like below quote.
The project aims to capitalize on the popularity of meme coins, like Shiba Inu and Dogecoin, and strives to establish itself as one of the top meme-based cryptocurrencies. PEPE appeals to the cryptocurrency community by instituting a no-tax policy, a redistributive system rewarding long-term stakers, and a burning mechanism to maintain scarcity of the PEPE coin.
I've won a number of SLP memes and I've kept them until now, even though the current price is $0.002, that's the only meme I got in betting gambling.
For me it's the same with the PEPE meme, there's nothing wrong with winning as much as you can in gambling for PEPE meme coins, if the casino has them, who knows in the next 5-10 years it will be like Doge, note: try to get the PEPE meme only in gambling bets, don't buy it specifically on purpose.