If you are going to wager as much as possible with slot games, min bet does affect the result.
Simple example, you have starting balance of $100 and you want to wager $10k.
The chance to reach the goal is better if you bet smaller lets say 0.1-0.2 than betting bigger amount like $5-$10.
Real example, I participated in a contest some time ago and I made 200k bets with $0.01 bet means I have wagered $2,000 while I started it with less than $50.
I believe I wont reach $2,000 wager if I bet more than $0.5 per spin as I may lose my initial bankroll sooner.
However if the main purpose is to compete wagering contest, it is obvious that small bets wont have chance to win but I think the main idea from ralle14 is about how to wager much with less risk of losing much.