If day trading, obviously different rules apply, If the price hits your chosen stop loss, the best thing to do is to sell as soon as possible, This also applies to when the price hits your desired target.
I also usually hold and prefer to do that, but in case urgent requirement, I do sell or spend my Bitcoins. I would advice the same actions to perform, sell only if its necessary. I am talking about the Bitcoins you acquired by selling goods or services, and if you are investing then mostly you should not require to sell as you should have known your requirements before investing.