I don't think a state, for instance, is overly specific. It determines a lot about the form and viability of the business. Take a look at all the different laws out there:
http://en.wikipedia.org/wiki/List_of_smoking_bans_in_the_United_StatesIn a state like North Carolina you could open a hookah lounge but not be able to serve food.
Statewide ban on smoking in bars, restaurants, and some other workplaces: On January 2, 2010, after being signed into law by Governor Bev Perdue on May 19, 2009, North Carolina Session Law 2009-27 went into effect, banning smoking statewide in all bars and restaurants in North Carolina, as well as in government buildings and vehicles.[271] The law exempts cigar bars, private clubs that are not-for-profit (including country clubs), designated hotel/motel smoking areas, and medical research facilities studying tobacco.[271] The law generally allows local governments to regulate smoking more strictly beginning July 5, 2009 (as long as it is approved by the county, too), but preempts local governments from regulating smoking in cigar bars, retail tobacco shops, tobacco manufacturer facilities, designated hotel/motel smoking rooms, private clubs (including country clubs), theatrical productions involving smoking, private residences, or private vehicles.[271]
In a state like Wyoming it would be no problem.
No statewide smoking ban. Instead, Wyoming state law only prohibits smoking where it could cause an explosion[380][381][382] and in underground mines.[383] Wyoming has no state laws concerning indoor smoking in general, and thus local governments can regulate general indoor smoking as they see fit. As of April 2009, five cities in Wyoming have enacted local smoking bans, all covering all bars and restaurants, but varying otherwise.[4] In February 2009, a bill before the Wyoming Legislature that would have enacted a statewide ban on smoking in all enclosed workplaces, except in private offices and in bars and restaurants serving only patrons over 21 years of age (and except in any local community that chose to opt out) failed when it was passed by the Wyoming House of Representatives in a vote of 31–29 but then was denied a committee hearing in the Wyoming Senate.[384]
Whereas in a state like Wisconsin you would not be able to do it at all.
Statewide smoking ban: On July 5, 2010, after being signed into law by Governor Jim Doyle on May 18, 2009, S.B. 181 (2009 Wisconsin Act 12) took effect, banning smoking statewide in all enclosed workplaces in Wisconsin, including all bars, restaurants, lodging establishments, and private clubs, as well as within a "reasonable distance" outdoors from any such place, except in bar/restaurant outdoor patios.[378] The Act exempts only cigar bars or retail tobacco stores already in existence, private residences, and rooms in nursing homes in which the occupants agree to allow smoking;[378] it does not cover casinos run by Native American tribes, as those casinos are in the tribes' sovereign territory. Local governments are preempted from regulating smoking more strictly than the Act.[378] Prior to this law taking effect, several localities in Wisconsin had local smoking bans in effect.
And of course any local area may have their own regulations as well. Hard to determine a level of interest without some general location information.