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Topic: [ANN] CureCoin 2.0 is live - Mandatory Update is available now - DEC 2018 - page 77. (Read 696267 times)

full member
Activity: 153
Merit: 100
I had the same thing happen to me. Been waiting about 20 hours for confirmation and 9 hours for a response from support.
staff
Activity: 3472
Merit: 4111
Crypto Swap Exchange
Does anyone have any idea why Cure withdrawals and deposits are temporarily disabled on Poloniex?
Some strange problems...
newbie
Activity: 37
Merit: 0
Does anyone have any idea why Cure withdrawals and deposits are temporarily disabled on Poloniex?
newbie
Activity: 37
Merit: 0
Thanks assistresearch.

I see that gridcoin has a lot of protein folding BOINC projects listed in their whitelist:
GPUGRID: Full-atom molecular simulations of proteins.
Poem@Home: Models protein folding using Anfinsen's dogma.
FIND@Home: docking simulations on malaria proteins

How does Folding@Home differ from these?

Folding@Home is a more mature project, its been running for over 15 years. It leads the field in developing new methods of simulation. It has the most reliable/useful software client, and more published research than all the projects you mentioned combined.

Basically everything used in the world of protein folding DCN's was primarily developed because of the Folding@home project.

It was a collaboration between F@H and ATi over 10 years ago that first looked at the possibilty of usings gpu's to do work that had always previously been done on a single core cpu.
It was F@H that developed the systems to use multicore cpus


Very good points Wilding2004 ... Folding@Home and Rosetta@home are often referred to as "complementary", however on a sheer level of computational research power, Folding@Home overshadows all BOINC projects combined (including the non-medical ones) in terms of PFLOPS by nearly 2.4x today (it has been over 4x within the last 18 months). So that in part determines the number of computations represented by each coin - if that helps. Some projects like GPUGRID are great, but have been known to occasionally run out of work, but that doesn't make their research any less interesting. I would say if you want to throw some power at some of those, it only helps the overall cause. I do it too - but coin-wise, I'm biased to CURE - I do buy GRID opportunistically just to stay diversified like assistresearch says.

Agreed.

Most of the protein simulation DCN's are doing similar science, but sometimes the smallest difference can be significant. For example Rosetta@home is primarily concerned with determining the final folded state of a protein, whereas Folding@home simulates the stages prior to the final state in order to understand the role of "mis-folding" in disease.
newbie
Activity: 29
Merit: 0
Thanks assistresearch.

I see that gridcoin has a lot of protein folding BOINC projects listed in their whitelist:
GPUGRID: Full-atom molecular simulations of proteins.
Poem@Home: Models protein folding using Anfinsen's dogma.
FIND@Home: docking simulations on malaria proteins

How does Folding@Home differ from these?

Folding@Home is a more mature project, its been running for over 15 years. It leads the field in developing new methods of simulation. It has the most reliable/useful software client, and more published research than all the projects you mentioned combined.

Basically everything used in the world of protein folding DCN's was primarily developed because of the Folding@home project.

It was a collaboration between F@H and ATi over 10 years ago that first looked at the possibilty of usings gpu's to do work that had always previously been done on a single core cpu.
It was F@H that developed the systems to use multicore cpus


Very good points Wilding2004 ... Folding@Home and Rosetta@home are often referred to as "complementary", however on a sheer level of computational research power, Folding@Home overshadows all BOINC projects combined (including the non-medical ones) in terms of PFLOPS by nearly 2.4x today (it has been over 4x within the last 18 months). So that in part determines the number of computations represented by each coin - if that helps. Some projects like GPUGRID are great, but have been known to occasionally run out of work, but that doesn't make their research any less interesting. I would say if you want to throw some power at some of those, it only helps the overall cause. I do it too - but coin-wise, I'm biased to CURE - I do buy GRID opportunistically just to stay diversified like assistresearch says.
hero member
Activity: 799
Merit: 1000
Can someone ask https://www.worldcoinindex.com/ to change the market cap

its completly wrong their is only +/-5m coins out there

The problem is due to the pre-mine that is allocated for folding payouts, this will only be fixed after cc2.0 launches.
full member
Activity: 164
Merit: 100
Can someone ask https://www.worldcoinindex.com/ to change the market cap

its completly wrong their is only +/-5m coins out there
newbie
Activity: 37
Merit: 0
Thanks assistresearch.

I see that gridcoin has a lot of protein folding BOINC projects listed in their whitelist:
GPUGRID: Full-atom molecular simulations of proteins.
Poem@Home: Models protein folding using Anfinsen's dogma.
FIND@Home: docking simulations on malaria proteins

How does Folding@Home differ from these?

Folding@Home is a more mature project, its been running for over 15 years. It leads the field in developing new methods of simulation. It has the most reliable/useful software client, and more published research than all the projects you mentioned combined.

Basically everything used in the world of protein folding DCN's was primarily developed because of the Folding@home project.

It was a collaboration between F@H and ATi over 10 years ago that first looked at the possibilty of usings gpu's to do work that had always previously been done on a single core cpu.
It was F@H that developed the systems to use multicore cpus
member
Activity: 66
Merit: 10
Thanks assistresearch.

I see that gridcoin has a lot of protein folding BOINC projects listed in their whitelist:
GPUGRID: Full-atom molecular simulations of proteins.
Poem@Home: Models protein folding using Anfinsen's dogma.
FIND@Home: docking simulations on malaria proteins

How does Folding@Home differ from these?
legendary
Activity: 1484
Merit: 1004
Hum well I really wanted to create a pi cluster  Tongue learning at the same time.
Will try to check with the pine 64  Wink
newbie
Activity: 29
Merit: 0
Any idea if a pi cluster could work fine at folding?  Grin

I don't believe the raspberry pi's ARM processor is supported for Folding@Home except for Android phones ...

I've read about people using MSFT compute sticks or you can pick up a cheap used laptop  (like one with a cracked screen), and use it to fold NaCl and concurrently staking your wallet.

I just learned about JaguarBoard (Intel x86 based raspberry pi alternative) This might actually work ... for VERY lightweight folding.

The only thing I would think a pi II could be used for, is to run the Android 4.4+ client for folding (no CureCoins from that client however... Sad

You probably already realize that even a 10 year old PC can be fitted with a modern video card, and put up some decent numbers.

Check out the folding calculator for PC, Mac or cloud equipment. That being said, your goals are probably cost and power efficiency ... like having a small device installed inline with each light bulb socket in the house - contributing to research and earning CURE.
newbie
Activity: 37
Merit: 0
Any idea if a pi cluster could work fine at folding?  Grin

Short answer is no.

For a slightly more detailed answer see this thread.
https://foldingforum.org/viewtopic.php?f=16&t=28440
legendary
Activity: 1484
Merit: 1004
Any idea if a pi cluster could work fine at folding?  Grin
newbie
Activity: 21
Merit: 0
I didn't even notice that gridcoin exploded the last few months. Did anyone here catch that train? I should've bought.. any guess on what they have that we don't? They claim to be decentralized, but I'm not sure. Can anyone confirm that?

Any science coin is only as decentralized as the source of its proof of work (in this case, distributed University Consortiums (Stanford or Berkeley)).

Their initial model (GridCoin Classic) was somewhat inefficient, and suffered from a few damaging hacker attacks. They switched to a decentralized blockchain model (they call it proof of research) by April 2015 which induced some further growing pains, but it looks like they stabilized the wallets. Their security algo I believe is based on Peercoin (like CureCoin) but they got rid of their pre-mine. CureCoin's decentralized 2.0 design has a more ambitious quantum-computer-proof algo (and a mini-blockchain designed for faster transactions), as such it has taken longer to implement in order to avoid being a "me too" decentralized science coin and to avoid introducing unnecessary churn. Notice CURE has only needed one security update since inception, Gridcoin has had numerous wallet updates to patch security and usability issues. This stuff isn't childs-play Smiley

This is just my biased opinion, and I do participate in Gridcoin myself - Crunchers have many projects to chose from on BOINC, and as such tend to concentrate crunching on projects which award the most points (or that they personally decide are worth-while). They aren't necessarily medical research related (like Rosetta@Home, or WGC), instead Milky Way seemed to be high on the list of priorities last I checked. While Milky Way is a very interesting distributed computing model predicting orbital mechanics of our galaxy, projects like it don't necessarily address more immediate needs, yet can be a priority for Grid crunchers.

An interesting dilemma with pure medical research - I've recently tried convincing a couple of people into Folding@Home participation (not even talking about coins), but they'd rather use their computational power to help SETI since they feel folding proteins only serves to help Big Pharma, as misguided as that may be. FAH results are made public.

Gridcoin valuation represents a POW on a mixture of diverse projects. Due to this diversity, Grid's user-base is broader. But their computational output in PetaFLOPs is lower due to most projects being CPU rather than GPU based (someone correct me if I'm wrong). In fact the CureCoin team at one point was producing more PetaFLOPs than the entire BOINC network (not just Grid) primarily due to the efficiency and optimization of GPU folding.

In conclusion - you have several choices in the Science Coin realm, and diversification is never a bad thing where financial matters are a concern.
member
Activity: 66
Merit: 10
I didn't even notice that gridcoin exploded the last few months. Did anyone here catch that train? I should've bought.. any guess on what they have that we don't? They claim to be decentralized, but I'm not sure. Can anyone confirm that?
newbie
Activity: 29
Merit: 0

troll. the folding coins helps humanity more than all coins

my Nvidia working on http://fah-web.stanford.edu/cgi-bin/fahproject.overusingIPswillbebanned?p=9212
Cystic fibrosis (CF).
can't stop it and mine shitcoins for profits


If that is so.. then why did you remove the link I had posted ?

Are you afraid of the information provided there ?

Do you mind if I call you Mr. Quack ?


yes you can call me Mr. Quack
i didn't want the whole image posted in quote
and yes the link scares me

and i wish someone will find the ultimate cure to kill cancer

You are not making any sense.

Why does proof that cures and preventative measures exist, scare you ? lol


I don't think "scared" is the right word here ... more like "concerned".

I do not doubt doctors and veterinarians have stumbled on effective herbal cures for some carcinomas in some patients. But your original question "Still looking.. I mean folding eh ?" suggests all research could stop, if only we could find these lost herbal formulas, while never needing to study the underlying mechanisms by which cancer first takes root.

You're also assuming Folding@home and other DCN research only covers cancer. What about Alzheimer's, Parkinson's, ALS, HIV, Malaria, Ebola, and Pandemic Influenzas?

The cancer statistics from the Latin American countries mentioned in the video are admittedly low - but then again, so are their life expediencies (they are dying of other diseases first) furthermore living an agrarian lifestyle exposes individuals to fewer industrial chemicals and processed foods.

The theory that a one-size-fits-all treatment for all carcinomas ignores the cause and effect. There is no single form of "cancer". One doesn't really have cancer, one is "cancering". There are interactions (or lack of interactions) between oncogenes and tumor suppressor genes (see list below). Each individuals body and tumor do not react equally to every cure presented. Dr. Hoxey claimed that those who failed his treatments merely had a "bad attitude".

One of the ultimate goals of cancer research (not the only goal) presented by Folding@Home is to enable the design of personalized medicines coded to individual patient's bodies. We do not only differ from eachother genetically, but also epigenetically (those are the proteins outside of the cell's nucleus). Those variations between humans (even between twins) can be practically infinite, leading to a need for individualized solutions for optimal results.

Notice that many of the over 500 projects studied by Folding@home cover natural compounds like Bryostatin (a natural deep-sea compound showing unique activity against cancer, HIV/AIDS, and Alzheimer's). The results of all those studies are made PUBLIC! Also, some of the projects deal with subjects outside the "human condition" such as custom enzyme designs to create bio-fuels more efficiently and perhaps, in the future, a cure for the Yellow Dragon virus plaguing citrus crops - causing massive damage and raising food prices.

Hippie Tech, I appreciate the video and I agree the pharma industry has many elements of corruption  - but do you feel because of that, we should stop learning about life science and go back to randomly applying herbal remedies and basing results on anecdotal evidence as they did in the 18th century and before?

I really hope you can join us in the quest for knowledge (and get paid in CURE  Smiley )


List of some Oncogenes:

PDGF Codes for platelet-derived growth factor. Involved in glioma (a brain cancer)
EGFR Codes for the receptor for epidermal growth factor. Involved in glioblastoma (a brain cancer) and breast cancer
HER-2 or ERBB2. Codes for a growth factor receptor. Involved in breast, salivary gland and ovarian cancers
RET Codes for a growth factor receptor. Involved in thyroid cancer
KRAS Involved in lung, ovarian, colon and pancreatic cancers
NRAS Involved in leukaemias
MYC1 Involved in leukaemias and breast, stomach and lung cancers
NMYC Involved in neuroblastoma (a nerve cell cancer) and glioblastoma
LMYC Involved in lung cancer
BCL2 Codes for a protein that normally blocks cell suicide. Involved in follicular B cell lymphoma
CCND1 or PRAD1 Codes for cyclin D1, a stimulatory component of the cell cycle clock. Involved in breast, head and neck cancers
CTNB1 Codes for beta-catenin, involved in liver cancers
MDM2 Codes for an antagonist of the p53 tumor suppressor protein. Involved in sarcomas (connective tissue cancers) and other cancers

List of some Tumor Suppressor Genes:
APC Involved in colon and stomach cancers
DPC4 Codes for a relay molecule in a signalling pathway that inhibits cell division. Involved in pancreatic cancer
NF-1 Codes for a protein that inhibits a stimulatory (Ras) protein. Involved in neurofibroma and pheochromocytoma (cancers of the peripheral nervous system)
and myeloid leukemia
NF-2 Involved in meningioma and ependymoma (brain cancers) and schwannoma (affecting the wrapping around peripheral nerves)
CDKN2A or MTS1 Codes for the p16 protein, a braking component of the cell cycle clock.
Involved in a wide range of cancers
RB1 Codes for the pRB protein, a master brake of the cell cycle. Involved in retinoblastoma and bone, bladder, small cell lung and breast cancer
TP53 Codes for the p53 protein, which can halt cell division and induce abnormal cells to kill themselves. Involved in a wide range of cancers
WT1 Involved in Wilms’ tumour of the kidney
BRCA1 Involved in breast and ovarian cancers
BRCA2 Involved in breast cancer
VHL Involved in renal cell cancer

 
legendary
Activity: 1624
Merit: 1001
All cryptos are FIAT digital currency. Do not use.
Still looking.. I mean folding eh ?


https://youtu.be/Tx7W662gd8M

troll. the folding coins helps humanity more than all coins

my Nvidia working on http://fah-web.stanford.edu/cgi-bin/fahproject.overusingIPswillbebanned?p=9212
Cystic fibrosis (CF).
can't stop it and mine shitcoins for profits


If that is so.. then why did you remove the link I had posted ?

Are you afraid of the information provided there ?

Do you mind if I call you Mr. Quack ?


yes you can call me Mr. Quack
i didn't want the whole image posted in quote
and yes the link scares me

and i wish someone will find the ultimate cure to kill cancer

You are not making any sense.

Why does proof that cures and preventative measures exist, scare you ? lol
newbie
Activity: 21
Merit: 0
I lost so many BTC on this coin lets hope we have better days ahead

SNAP me too. This could have been an amazing project. They pretty much dropped the ball on this one.

Usually FUD is introduced in financial markets when people want to exert selling pressure so they can "back up the truck" and load up :-)
But OK, fair enough - nobody is happy about the valuation when everyone is aware of how much goes into folding:

But, “dropped the ball”!? In two years they've been:

  • Listed on over three exchanges, including livecoin (which allows BTC to fiat exchange)
  • Available on coinpayments.net … exposing CURE to over 18,000 potential vendors
  • Set records in Work Units & Points Produced by a single team in the shortest time
  • Very minimal security breaches (the IRC bot incident) unlike other coins in the same space
  • Ongoing communications with retailers and charities (if you watch social media)
  • Periodic media articles (most recently in Finance Magnates)
  • Practically all self-funded by the core team
  • Attending several Bitcoin conferences plus participated in a Tedx
  • Influential force: TM's actively participate on folding forums & folding reddits (and in FAH beta testing)
  •   Actually introduced the idea of CureCoin funding new research in the future
  • Fast assistance on the forum from a supportive community
  • And yes, 2.0 is still in beta, BUT you can download it from testnet and become a beta tester.

If you have a lot of skin in the game, let’s ask some questions:

  • Have you done anything to promote the fundamental principles that underly CureCoin's value?
  • Made any social media posts about CureCoin’s potential lately?
  •     Look what Andreas Antonopoulos does for Bitcoin, and he’s not even a core dev!!!
  • Talked to local businesses into accepting CURE, or give discounts to folders?
  • Have you given CURE wallets to friends and family?
  • Donated any CURE to the addresses published on the homepage over the last year?
  • Are you staking your wallet to help secure the network?
  • Are you folding?

Sorry - had to chime in on this thread. Hopefully this didn't come off as a rant - I'm just trying to remind people of all the accomplishments rather than dwelling purely on valuation. I had a conversation with a friend who really KNOWS PEOPLE. He loves this project as many of us do, but after attending a retreat with his company in LA, where the key-note speaker was a famous geneticist, he looked around and noticed - no one was paying attention. He concluded (paraphrasing here, he used harsher language) " just aren't yet savvy enough to grasp the concept of protein folding - let alone adding a crypto-currency layer like CureCoin on top of it"

With the right exposure, this can be much more than a "coin", it can be a global movement against a common enemy - disease.
It just takes time for these things to crystallize in people's minds in an instant gratification world. Hopefully sooner than later.

Cheers!

first they ignore you, then they laugh at you, then they fight you, then you win.
sr. member
Activity: 397
Merit: 251
CureCoin Lead Dev
A quick note on some items from news links, as many have noticed, news outlets sometimes take their own spin on things, like the title to this interview:

http://www.financemagnates.com/cryptocurrency/interview/curecoin-founder-my-cryptocurrency-can-end-all-disease-in-100-years/#

"curecoin founder: my cryptocurrency can end all disease in 100 years"

They took a bit of a creative license on the title, not my words, but it sure would be neat wouldn't it?

The interview itself is an ok read. I was up late compiling openssl on a fresh Linux build for compiling when the interviewer caught up with me. The interview only covers about 1/3 of what I'd like to have published about CureCoin.

The team is working on some informative videos, some of which you can already find in our community links, and social media pages like facebook.com/curecoin and @CureCoin_Team .
sr. member
Activity: 397
Merit: 251
CureCoin Lead Dev
Updated OP

Added some vendor information, link to coinpayments.net if you want to accept cure or shop with cure.

Added some direct vendor links accepting CureCoin

Added a few of the many news references to CureCoin

minor other changes...

For those looking for more information please follow community links in OP to get involved or just do some reading about the project.

and i wish someone will find the ultimate cure to kill cancer

Well said Wink
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