Important! A new option was added: --difficulty-multiplier. It allows to set stratum difficulty multiplier. For QubitCoin, Quark and Animecoin it will be usually 256. For Groestlcoin, Fuguecoin and Twecoin it will be usually 0.0039062500 (1/256). Default value is 1.0. If you have "share above target" errors then set it to 256. If difficulty required by pool is strangely large, set it to 0.0039062500 (1/256). Other values are unlikely to be used. Hopefully this will fix all remaining stratum problems.
I looked into this more and it depends on which pool you mine from. If you get too many accepts going on, you need to raise it. If you don't see any accepts, you need to lower it. I would guess you should see about 1 accept every 30 seconds would be good. You don't want the pool to get overloaded with accepting shares and you want to submit your work at least once per block.