You can block for vitamin D receptor if you take more vitamin D than needed.
You need labs before considering megadosing, since it can be harmful. One of the few vitamins you can megadose on is k2 since it doesnt get stored and most people have a deficiency.
Look I am suffering from Multiple Sclerosis. I tried all sorts of remedies since 2012. The only remedy which put my M.S. into remission in 2012 and 2013 was high dose vitamin D3. In both instances, I stopped the treatment due to fear of permanent renal damage. As of March 2015, I became desperate because my condition was progressively deteriorating and worse yet I couldn't get any serious work done and my life and opportunities were slipping away from me.
Since the end of March, I have been taking daily doses of vitamin D3 that average greater than 30,000 IU per day. I have also been drinking about 2 - 3L of water per day to flush out my kidneys (and urinating like a sieve), "B Natural" co-enzymated B complex occasionally, Kelp tablets daily for iodine, and dark leafy greens equivalent to spinach daily (as well as any other foods I like).
This treatment has given me the energy to program up to 18 hours per day and release a new social network. It appears to have lowered my EDSS symptoms index from roughly 5 to roughly 3.
The Brazilian neurologist (graduated and interned in the USA) claims to have cured 95% of the 2500+ autoimmunity (mostly Multiple Sclerosis) patients he has treated over the past 15 years or so, by employing this high dose vitamin D3 treatment. Note he requires the patient to see a doctor who has been trained on this protocol. I unfortunately can't afford the expense and time lost to see one of his apprentices. So I am winging it and not thrilled about that. Hopefully I can soon have enough money and free time to get professional oversight.
Glad it worked for you, im just saying I dont see it as a general good advice to tell people to megadose around on D3, maybe for certain cases it is a good idea.
Whats the name of that Brazilian neurologist?
Find it on the vitamin D wiki (google). I am very rushed at the moment..