10000% YES, as long as you keep the seed generated on initial setup in safe storage on a piece of paper.
BOP, myTrezor, the TREZOR itself, sathosilabs, they can all blow up and dissapear from the face of the planet...
With https://dcpos.github.io/bip39/, you can create all your private keys and import them old school in even an old version of Bitcoin-qt.
They should all be safe there, but I am never a proponent of keeping all of your coins in one spot. I would recommend keeping a little on blockchain.info (because of convenience), and maybe some on another client like electrum or bitcoin core, etc. If all of your coins are on the trezor, and you want to spend money (and you don't have the physical trezor), then you are unable to spend/send any coins.