I guess their main targets could be Kane and Mbappe right now. They really want to strengthen their attacking line and it would be great to see one of these players at Real Madrid. It looks like Mbappe transfer will be a very tough one for them as PSG don't want to let him go at all. So, they could give up on him and make an effort to sign Kane.
They can get Mbappe but not too easy because PSG know how great Mbappe is and how he is important for them. They don't actually need money and they will do the best to keep Mbappe in Par de Princes.
Kane is different, he want to leave, Spurs will not be able to keep him in White Hart Lane but Kane does not want to leave Premier League. His plan will prevent the transfer with Real Madrid.
believe it or not, I firmly believe that if Ramos left the club Real Madrid would find a replacement very quickly, they have a wealth of data on talented players.
Reportedly, Real Madrid are in negotiations with Sevilla to sign French centre-back Jules Kunde.
Even Ancelotti was willing to put aside discussions about Mbappe, Haaland and Lozano.
Ramos can play good in next 2 to 3 seasons and like Thiago Silva in Chelsea, he can be a good leader in a new club. I don't think with the tradition of Real Madrid and Florentino Perez, they will let Ramos leave the club and find another younger player.