There is a new interesting coin called talkcoin that looks to be ASIC resistant and even Profit Switching resistant.. How exactly it does this, I am not sure. But it sounded interesting.
TalkCoin is just scrypt PoW Litecoin clone with 20 second block times (a dumb idea) randomized block rewards (like Doge), and community-vote-chosen block rewards (from Heavycoin).
It does include a built-in decentralized chat (lol! seriously - the client connects to IRC already)... but it isn't ASIC or profit switching resistant.
(Unless I read the code for the wrong talkcoin-wallet)
It's important to remember that nothing is actually ASIC or profit-switching proof - some systems simply resist these forces by developing new solutions that haven't been countered yet. Anything that can be mined with a CPU or GPU can be mined more efficiently with ASIC equipment. It is simply a matter of cost/benefit - is it worth producing ASICs for a given algorithm?
And I am extremely confident there will be a multi-algorithm auto-switching pool for GPU miners our this year - very likely before Q4. Development is already underway. (Hint: the stratum protocol will almost certainly be replaced this year)