I think Chelsea's advantage is that, the next game will be against Lille. Last year, they only started to have good games in the finals of the season, the same can happen now. So, with a more accessible game for this stage of the season, you can help your growth.
We must also not forget that Chelsea are simply the reigning cup holders in this tournament. Last season they certainly didn't start the tournament as favorites, but in the end they deserved to win. I'm not ruling out a surprise this year either. They also now have a favorable draw. You have to be lucky with draw and then be at your best 2x against a good opponent. Chelsea used to play boring football, that has changed under Lampard and now under Tuchel, and it also delivers good performances.
ya.ya.yo!